林奇综合征患者妇科恶性肿瘤筛查和预防的现状或不足。

IF 1.4 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Clinical obstetrics and gynecology Pub Date : 2024-12-01 Epub Date: 2024-10-18 DOI:10.1097/GRF.0000000000000892
Sharonne Holtzman, Madison Cox, Stephanie V Blank
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引用次数: 0

摘要

林奇综合征(LS)是一种常染色体显性遗传疾病,会导致罹患卵巢癌和子宫内膜癌的风险增加。本文旨在探讨如何通过筛查和预防来控制这一风险。本文对已发表的资料和证据进行了探讨和总结。本文表明,虽然人们对LS患者的识别和诊断有了更多的认识和进步,但筛查和预防的建议仍然缺乏证据基础。在对LS患者进行管理决策时,应考虑患者的个体目标,采用共同决策模式。
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The Current State-or Lack Thereof-of Screening and Prevention for Gynecologic Malignancies for Patients With Lynch Syndrome.

Lynch syndrome (LS) is an autosomal dominant genetic disorder that results in an increased risk of ovarian and endometrial cancers. The aim of this paper was to explore the management of this risk through screening and prevention. Published materials and evidence were explored and summarized. This paper demonstrated that while there has been increased awareness and advances in the identification and diagnosis of patients with LS, recommendations for screening and prevention remain less evidence-based. In decisions of management of patients with LS, a shared decision-making model should be used considering individual patient goals.

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来源期刊
CiteScore
2.70
自引率
0.00%
发文量
186
审稿时长
3 months
期刊介绍: Each issue of Clinical Obstetrics and Gynecology is a complete symposium on one or two timely topics of interest in obstetrics and gynecology. For each quarterly issue, two prominent guest editors solicit contributions on key clinical topics of interest to practicing physicians. Procedures, current clinical problems, medical and surgical treatments, and effective diagnostic aids are all carefully reviewed in original articles. The result is an instructive resource that dispenses trustworthy clinical guidance that enhances your understanding of key areas of your practice.
期刊最新文献
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