临床实践指南:下颌骨髁状突增生--诊断与治疗》。

IF 6.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Deutsches Arzteblatt international Pub Date : 2024-12-13 DOI:10.3238/arztebl.m2024.0210
Merle Riechmann, Nils-Claudius Gellrich, Bodo Kress, Christopher Schmidt, Cornelia Schröder, Andreas Neff
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引用次数: 0

摘要

背景:下颌骨髁状突增生的特点是髁状突的大小和形态异常。在德国,经诊断和/或治疗的髁状突增生症的行政发病率为每 10 万人 2.4-9.6 例。误诊很常见,可导致严重的美学和功能性并发症,包括面部畸形(可发展到患者 20 多岁)以及语言和咀嚼功能障碍:方法:我们对文献进行了系统性的回顾,并采用德尔菲法进行了结构化共识调查:结果:专家建议及时诊断髁状突增生,以便通过适当的治疗防止其恶化。基本诊断评估包括病史采集、体格检查和正位影像学检查。如果确诊为髁状突增生,则需要进行三维成像,通常使用 SPECT。治疗方法主要是外科手术:髁突部分切除术和正颌外科手术是最常见的方法。如果不及时治疗,这种疾病会导致严重的咀嚼功能障碍和毁容。大多数关于髁状突增生症治疗方法的研究都是基于较少的病例数,且仅获得了 4 级或 5 级证据:结论:髁状突增生是一个常见的问题,但并不广为人知。早期诊断和治疗可避免严重的下颌不对称和进一步的并发症,如颅颌关节功能障碍和颞颌关节关节炎。
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Clinical Practice Guideline: Condylar Hyperplasia of the Mandible—Diagnosis and Treatment.

Background: Condylar hyperplasia of the mandible is characterized by abnormal size and configuration of the condylar process. In Germany, the administrative prevalence of diagnosed and/or treated condylar hyperplasia is 2.4-9.6 cases per 100 000 persons. Misdiagnosis is common and can lead to severe esthetic and functional complications, including facial deformity that can progress into the patient's twenties, as well as dysfunctional speech and mastication.

Methods: We conducted a systematic review of the literature and a structured consensus-finding process with the Delphi method.

Results: The experts recommend timely diagnosis of condylar hyperplasia so that its progression can be prevented by appropriate treatment. The basic diagnostic evaluation consists of history taking, physical examination, and imaging with orthopantomography. If condylar hyperplasia is confirmed, three-dimensional imaging is performed, usually with SPECT. The treatment is mainly surgical: partial condylectomy techniques and orthognathic surgery are the most common methods. If left untreated, the disorder causes severe dysfunction of mastication as well as disfigurement. Most studies of treatments for condylar hyperplasia have been based on low case numbers and have yielded only level 4 or level 5 evidence.

Conclusion: Condylar hyperplasia is a common, but not widely known problem. Its early diagnosis and treatment can prevent severe jaw asymmetry and further complications such as craniomandibular dysfunction and arthrosis of the temporomandibular joints.

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来源期刊
Deutsches Arzteblatt international
Deutsches Arzteblatt international 医学-医学:内科
CiteScore
4.10
自引率
5.20%
发文量
306
审稿时长
4-8 weeks
期刊介绍: Deutsches Ärzteblatt International is a bilingual (German and English) weekly online journal that focuses on clinical medicine and public health. It serves as the official publication for both the German Medical Association and the National Association of Statutory Health Insurance Physicians. The journal is dedicated to publishing independent, peer-reviewed articles that cover a wide range of clinical medicine disciplines. It also features editorials and a dedicated section for scientific discussion, known as correspondence. The journal aims to provide valuable medical information to its international readership and offers insights into the German medical landscape. Since its launch in January 2008, Deutsches Ärzteblatt International has been recognized and included in several prestigious databases, which helps to ensure its content is accessible and credible to the global medical community. These databases include: Carelit CINAHL (Cumulative Index to Nursing and Allied Health Literature) Compendex DOAJ (Directory of Open Access Journals) EMBASE (Excerpta Medica database) EMNursing GEOBASE (Geoscience & Environmental Data) HINARI (Health InterNetwork Access to Research Initiative) Index Copernicus Medline (MEDLARS Online) Medpilot PsycINFO (Psychological Information Database) Science Citation Index Expanded Scopus By being indexed in these databases, Deutsches Ärzteblatt International's articles are made available to researchers, clinicians, and healthcare professionals worldwide, contributing to the global exchange of medical knowledge and research.
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