早期诊断和监测阿尔茨海默病的新技术。

IF 3.4 2区 医学 Q2 CLINICAL NEUROLOGY Expert Review of Neurotherapeutics Pub Date : 2024-10-22 DOI:10.1080/14737175.2024.2415985
Parul, Animesh Singh, Shubha Shukla
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引用次数: 0

摘要

简介阿尔茨海默病(AD)是最常见的神经退行性疾病,以认知功能逐渐丧失为特征。阿尔茨海默病发病率高、病程长、多病共存,严重影响患者的生活质量和功能。早期发现和准确诊断阿尔茨海默病(AD)可以阻止病情发展,从而推迟症状的出现。因此,为了对阿尔茨海默病进行早期诊断和监测,需要更灵敏、无创、简便且经济实惠的筛查工具:本综述总结了早期检测方法的重要性以及可供医护人员使用的阿尔茨海默病诊断新技术:专家观点:早期诊断有助于患者和护理人员了解问题所在,共同制定合理的目标和未来计划。早期诊断技术不仅有助于监测疾病的进展,还能为开发新型治疗目标提供重要信息。研究人员可以计划通过识别早期分子变化和针对改变的通路,减轻阿尔茨海默病的症状或减缓其进展。
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Novel techniques for early diagnosis and monitoring of Alzheimer's disease.

Introduction: Alzheimer's disease (AD) is the most common neurodegenerative disorder, which is characterized by a progressive loss of cognitive functions. The high prevalence, chronicity, and multimorbidity are very common in AD, which significantly impair the quality of life and functioning of patients. Early detection and accurate diagnosis of Alzheimer's disease (AD) can stop the illness from progressing thereby postponing its symptoms. Therefore, for the early diagnosis and monitoring of AD, more sensitive, noninvasive, straightforward, and affordable screening tools are needed.

Areas covered: This review summarizes the importance of early detection methods and novel techniques for Alzheimer's disease diagnosis that can be used by healthcare professionals.

Expert opinion: Early diagnosis assists the patient and caregivers to understand the problem establishing reasonable goals and making future plans together. Early diagnosis techniques not only help in monitoring disease progression but also provide crucial information for the development of novel therapeutic targets. Researchers can plan to potentially alleviate symptoms or slow down the progression of Alzheimer's disease by identifying early molecular changes and targeting altered pathways.

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来源期刊
Expert Review of Neurotherapeutics
Expert Review of Neurotherapeutics Medicine-Neurology (clinical)
CiteScore
7.00
自引率
2.30%
发文量
61
审稿时长
4-8 weeks
期刊介绍: Expert Review of Neurotherapeutics (ISSN 1473-7175) provides expert reviews on the use of drugs and medicines in clinical neurology and neuropsychiatry. Coverage includes disease management, new medicines and drugs in neurology, therapeutic indications, diagnostics, medical treatment guidelines and neurological diseases such as stroke, epilepsy, Alzheimer''s and Parkinson''s. Comprehensive coverage in each review is complemented by the unique Expert Review format and includes the following sections: Expert Opinion - a personal view of the data presented in the article, a discussion on the developments that are likely to be important in the future, and the avenues of research likely to become exciting as further studies yield more detailed results Article Highlights – an executive summary of the author’s most critical points
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