一例非免疫力低下的脑瘫患者因帽状木兰霉菌感染肺部的病例

IF 2.9 3区 医学 Q2 INFECTIOUS DISEASES Infection and Drug Resistance Pub Date : 2024-10-11 eCollection Date: 2024-01-01 DOI:10.2147/IDR.S471082
Yanyan Jiang, Zhengzheng Chen, Huoyang Lv, Lihua Jiang, Zhiyuan Fan
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引用次数: 0

摘要

背景:帽状木兰霉(M. capitatus)是一种二形机会真菌,是一种罕见的酵母菌,在亚洲鲜有报道。由于缺乏既定的临床断点,这种真菌的治疗面临挑战:我们报告了一例罕见病例,患者是一名年轻的非免疫功能低下男性,患有脑瘫、脊柱畸形和肺部卡皮特氏酵母菌感染。患者在接受伏立康唑治疗后病情好转并趋于稳定:结论:卡皮氏霉菌感染通常与血液肿瘤和免疫力低下有关。在非免疫力低下的宿主患者中发生帽状真菌感染的报告并不常见。对这些真菌的认识不足可能会导致真菌感染诊断不足和临床误诊,从而可能导致治疗延误和死亡率升高。
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A Case of Pulmonary Infection Due to Magnusiomyces capitatus in a Non-Immunocompromised Patient with Cerebral Palsy.

Background: Magnusiomyces capitatus (M. capitatus) is a dimorphic opportunistic fungus that is a rare yeast and rarely reported in Asia. Owing to the absence of established clinical breakpoints, the treatment of this fungus poses challenges.

Case presentation: We report a rare case of a young, non-immunocompromised man with cerebral palsy, spinal deformity, and pulmonary M. capitatus infection. The patient's condition improved after treatment with voriconazole and became stable.

Conclusion: M. capitatus infection is commonly associated with hematologic tumors and compromised immunity. Reports of M. capitatus infection in patients with non-immunocompromised host are uncommon. Insufficient understanding of these fungi may lead to underdiagnosis of fungal infection and clinical misdiagnosis, potentially resulting in delayed treatment and increased mortality.

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来源期刊
Infection and Drug Resistance
Infection and Drug Resistance Medicine-Pharmacology (medical)
CiteScore
5.60
自引率
7.70%
发文量
826
审稿时长
16 weeks
期刊介绍: About Journal Editors Peer Reviewers Articles Article Publishing Charges Aims and Scope Call For Papers ISSN: 1178-6973 Editor-in-Chief: Professor Suresh Antony An international, peer-reviewed, open access journal that focuses on the optimal treatment of infection (bacterial, fungal and viral) and the development and institution of preventative strategies to minimize the development and spread of resistance.
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