食管癌伴小肠转移:病例报告与文献综述。

IF 0.5 Q4 ONCOLOGY International Cancer Conference Journal Pub Date : 2024-08-27 eCollection Date: 2024-10-01 DOI:10.1007/s13691-024-00717-y
Vigneshwaran Chandran, Kannan Periasamy, Lileswar Kaman, Kirti Gupta, Uma Nahar
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引用次数: 0

摘要

小肠转移极为罕见,迄今仅有 13 例报道,几乎所有此类患者都出现肠梗阻。转移性食管癌的 5 年总生存率低至 5%,而小肠转移患者尽管接受了小肠根治性切除术,但中位生存期仅为 3 个月(1-12 个月)。我们介绍了一例 50 多岁的男性患者,他出现吞咽困难已有 4 个月。经评估,他被发现患有中胸食管鳞状细胞癌。他在 5 周内接受了根治性化疗,每次 25 次,每次 60 Gy。治疗结束一周后,他出现回肠梗阻和网膜结节,手术切除并评估了相应的回肠段和网膜活检,发现了转移性鳞状细胞癌。患者于术后 3 个月去世。食管癌伴有小肠转移的预后非常差,尽管患者接受了切除手术,但很少能存活超过 1 年。因此,当这类患者出现肠梗阻的临床特征时,必须考虑小肠转移,以便早期诊断和积极治疗。
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Carcinoma esophagus with small bowel metastasis: a case report with review of literature.

Small intestinal metastasis is extremely rare and only 13 cases have been reported till date and almost all such patients have presented with intestinal obstruction. The 5-year overall survival for metastatic esophageal cancer is as low as 5% while the patients with small intestinal metastasis have a median survival of only 3 months (range 1-12 months) despite undergoing radical resection of the small bowel. We present a case of a male in his 50's who presented with difficulty in swallowing for 4 months. On evaluation, he was found to have squamous cell carcinoma in the mid thoracic esophagus. He underwent radical chemo-radiation up to 60 Gy in 25 fractions over 5 weeks. One week after completion of treatment he presented with ileal obstruction and omental nodules and surgical resection and evaluation of the respective ileal segment and omental biopsy revealed a metastatic squamous cell carcinoma. The patient expired 3 months post-surgery. Carcinoma esophagus with small bowel metastasis has a very grave prognosis that patients rarely survive beyond 1 year despite undergoing resection. Hence it is imperative to consider a small bowel metastasis when such patients present with clinical features of intestinal obstruction for early diagnosis and aggressive management.

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来源期刊
自引率
14.30%
发文量
57
期刊介绍: This online-only journal publishes original case reports on all types of cancer. In particular, we welcome not only case reports of educational value in the diagnosis and treatment of cancers, but also reports on molecularly analyzed cancer cases, including gene mutations, gene fusions, gene expression, and changes in copy number, regardless of their known clinical significance. Assessing the molecular analysis of a tumor usually requires a “cancer conference” in which experts from various fields discuss it. Even if the authors and their respective “cancer conference” were unable to determine the clinical significance of molecular changes at the time of submission and publication, their data may provide evidence that will help the scientific community develop precision medicine solutions in the future. We welcome case reports with reviews of the literature on similar cases, as they are more useful and valuable to readers than are reports of rare cases. International Cancer Conference Journal is the official publication of the Japan Society of Clinical Oncology (JSCO). - Presents an online-only collection of original case reports on all types of cancer - In particular, welcomes molecularly analyzed cancer cases - The Official Publication of the Japan Society of Clinical Oncology (JSCO)
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