与用药相关的角膜炎病例:一项基于人群的药物警戒研究

IF 2.6 3区 医学 Q2 OPHTHALMOLOGY Journal of cataract and refractive surgery Pub Date : 2025-01-01 DOI:10.1097/j.jcrs.0000000000001573
Ryan S Huang, Andrew Mihalache, Marko M Popovic, Clara C Chan
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引用次数: 0

摘要

摘要:角膜炎(Keratoconus,KC)与过敏症、结缔组织疾病和反复揉眼造成的机械性创伤有关。然而,表明某些药物可能会加重或诱发 KC 的证据在很大程度上仍局限于病例报告。这项基于人群的真实世界药物警戒分析旨在利用食品药品管理局不良事件报告系统(FAERS)的数据,全面调查药物与 KC 报告之间的关联。总体而言,有几种药物与过高的 KC 报告相关,包括性激素(如黄体酮和雌二醇)、奥洛帕他定、异维A酸、哌醋甲酯、螺内酯、抗精神病药(如阿立哌唑和利培酮)以及杜匹单抗。这些结果突出表明,临床上需要提高警惕,监测处方这些药物的患者是否出现 KC 的早期症状。此外,医疗服务提供者应意识到 KC 可能与药物有关,尤其是在高危人群中。
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Keratoconus cases associated with medication use: population-based pharmacovigilance study.
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来源期刊
CiteScore
5.60
自引率
14.30%
发文量
259
审稿时长
8.5 weeks
期刊介绍: The Journal of Cataract & Refractive Surgery (JCRS), a preeminent peer-reviewed monthly ophthalmology publication, is the official journal of the American Society of Cataract and Refractive Surgery (ASCRS) and the European Society of Cataract and Refractive Surgeons (ESCRS). JCRS publishes high quality articles on all aspects of anterior segment surgery. In addition to original clinical studies, the journal features a consultation section, practical techniques, important cases, and reviews as well as basic science articles.
期刊最新文献
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