遗传性出血性远端血管扩张症患者甲硝唑诱发脑病的罕见病例

IF 0.9 Q3 MEDICINE, GENERAL & INTERNAL Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2024-09-09 eCollection Date: 2024-01-01 DOI:10.55729/2000-9666.1398
Tina H Dao, Kinza Khan, Christopher D Jackson
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引用次数: 0

摘要

甲硝唑诱发脑病(MIE)是一种罕见的中毒性脑病。我们描述了一名遗传性出血性毛细血管扩张症(HHT)患者的可逆性甲硝唑诱发脑病病例,该患者因脑脓肿接受甲硝唑治疗后出现头晕、乏力、构音障碍和严重的构音障碍。他的脑磁共振成像(MRI)显示,在延髓橄榄核、小脑齿状核和背侧脑桥的双侧对称性病变区域强度增高,这些都是MIE的特征。停用甲硝唑后,患者的症状明显好转,随后的核磁共振成像显示病变消失。
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An Unusual Case of Metronidazole-induced Encephalopathy in a Patient with Hereditary Hemorrhagic Telangiectasia.

Metronidazole-induced encephalopathy (MIE) is a rare toxic encephalopathy. We describe a reversible MIE case in a patient with hereditary hemorrhagic telangiectasia (HHT), treated with metronidazole for brain abscess, who developed dizziness, weakness, dysarthria, and severe dysmetria. His Magnetic Resonance Imaging (MRI) brain revealed bilateral, symmetric lesions in bilateral symmetrical regions of increased intensity in the medullary olives, cerebellar dentate nuclei, and the dorsal pons, all characteristic of MIE. Upon metronidazole discontinuation, the patient experienced significant symptom improvement, with subsequent MRI showing resolution of the lesions.

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来源期刊
自引率
0.00%
发文量
106
审稿时长
17 weeks
期刊介绍: JCHIMP provides: up-to-date information in the field of Internal Medicine to community hospital medical professionals a platform for clinical faculty, residents, and medical students to publish research relevant to community hospital programs. Manuscripts that explore aspects of medicine at community hospitals welcome, including but not limited to: the best practices of community academic programs community hospital-based research opinion and insight from community hospital leadership and faculty the scholarly work of residents and medical students affiliated with community hospitals.
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