粘性复仇:IgA Lambda 多发性骨髓瘤高粘度综合征病例报告。

IF 0.9 Q3 MEDICINE, GENERAL & INTERNAL Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2024-09-09 eCollection Date: 2024-01-01 DOI:10.55729/2000-9666.1397
Afoma Onyechi, Jessica Ohemeng-Dapaah, Ayesha Kang, Alexandre Lacasse, Ranju Kunwor
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引用次数: 0

摘要

多发性骨髓瘤(MM)是一种相对少见的单克隆浆细胞增生性肿瘤。常见的表现是浆细胞浸润骨骼和其他器官,导致血清总蛋白浓度升高、高钙血症、肾损伤和贫血。最常见的 MM 类型是 IgG Kappa,其次是 IgA 亚型。血粘度过高(HVS)是 MM 的一种罕见表现,治疗方法包括及时进行血浆置换术,从而显著降低血清粘度并缓解症状。我们介绍了一例出现 HVS 的 IgA Lambda MM。
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Viscous Vengeance: A Case Report of Hyperviscosity Syndrome in IgA Lambda Multiple Myeloma.

Multiple myeloma (MM) is a relatively uncommon neoplastic proliferation of monoclonal plasma cells. Common manifestations are related to infiltration of plasma cells into bones and other organs, causing an increased total serum protein concentration, hypercalcemia, kidney injury, and anemia. The most common type of MM is IgG Kappa, and the second most common type is the IgA subtype. Hyperviscosity (HVS) is a rare presentation of MM and management includes prompt plasmapheresis, resulting in significant reduction of serum viscosity and symptomatic relief. We present a case of IgA Lambda MM presenting with HVS.

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106
审稿时长
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期刊介绍: JCHIMP provides: up-to-date information in the field of Internal Medicine to community hospital medical professionals a platform for clinical faculty, residents, and medical students to publish research relevant to community hospital programs. Manuscripts that explore aspects of medicine at community hospitals welcome, including but not limited to: the best practices of community academic programs community hospital-based research opinion and insight from community hospital leadership and faculty the scholarly work of residents and medical students affiliated with community hospitals.
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