Wesley W W Butt, Daniel R Wieland, Han Wang, Ching-Heng Lin, Jing-Jie Wang, Chien-Hsiang Weng
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引用次数: 0
摘要
目的:本研究旨在确定耳鸣病史是否与发展为痴呆的风险相关。方法:一项以全国人口为基础的病例对照研究,包括台湾所有符合条件的成年人。结果:共纳入15686例患者,病例组和对照组各7843例。有耳鸣病史的患者在65岁前被诊断为痴呆的风险较高(50岁≤年龄p = 0.017)。65岁及以上患者无统计学意义(校正优势比1.17,95% CI 0.90-1.51, p = 0.235)。结论:在50-65岁的人群中,耳鸣病史与被诊断为痴呆的风险增加168%有关。这种关联在65岁以上的人群中不显著。
Tinnitus and dementia risk: a nationwide population-based case-control study.
Objective: This study aimed to determine if a history of tinnitus is associated with the risk of developing dementia.
Method: A nationwide population-based case-control study including all eligible adults in Taiwan.
Results: A total of 15 686 patients were included in the study, with 7843 individuals making up each of the case and control groups. Patients with a history of tinnitus were associated with a statistically significant higher risk of being diagnosed with dementia before reaching 65 years old (50 years ≤ age <65 years) (adjusted odds ratio 2.68, 95 per cent confidence interval (CI) 1.19-6.05, p = 0.017). No statistical significance was found among those 65 years and older (adjusted odds ratio 1.17, 95 per cent CI 0.90-1.51, p = 0.235).
Conclusion: A history of tinnitus was associated with a 168 per cent increased risk of being diagnosed with dementia in those aged 50-65 years old. This association was not significant in those older than 65 years.
期刊介绍:
The Journal of Laryngology & Otology (JLO) is a leading, monthly journal containing original scientific articles and clinical records in otology, rhinology, laryngology and related specialties. Founded in 1887, JLO is absorbing reading for ENT specialists and trainees. The journal has an international outlook with contributions from around the world, relevant to all specialists in this area regardless of the country in which they practise. JLO contains main articles (original, review and historical), case reports and short reports as well as radiology, pathology or oncology in focus, a selection of abstracts, book reviews, letters to the editor, general notes and calendar, operative surgery techniques, and occasional supplements. It is fully illustrated and has become a definitive reference source in this fast-moving subject area. Published monthly an annual subscription is excellent value for money. Included in the subscription is access to the JLO interactive web site with searchable abstract database of the journal archive back to 1887.