比较两种不同仪器对肝细胞癌患者进行二维剪切波弹性成像的效果

IF 2.1 4区 医学 Q2 ACOUSTICS Journal of Ultrasound in Medicine Pub Date : 2025-02-01 Epub Date: 2024-10-14 DOI:10.1002/jum.16597
Jiayao Huang, Xiaoer Zhang, Liya Su, Ming Liu, Ming Xu, Bowen Zhuang, Baoxian Liu, Tongyi Huang, Hangtong Hu, Xiaohua Xie, Xiaoyan Xie, Manxia Lin
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引用次数: 0

摘要

研究目的本研究旨在调查和比较两种不同设备的二维剪切波弹性成像(2D-SWE)测量结果和影响因素,并评估这些测量结果评估肝纤维化的能力和影响因素:方法:自2022年10月至2023年9月,前瞻性地纳入了290名肝细胞癌(HCC)患者和30名健康志愿者。二维-SWE测量使用AixPlorer V(SEmean)和APLIO i900(CEmean)进行。本研究比较了不同仪器的二维-SWE测量结果,以评估肝纤维化分期,并分析了潜在的影响因素:结果:两种仪器获得的 2D-SWE 测量值差异显著(P .050)。多变量线性回归分析显示,独立影响 SEmean 的因素是丙氨酸氨基转移酶(ALT)(P = .034)和肝纤维化分期(P 结论:虽然两种仪器的 2D-SWE 测量值有显著差异(P.050),但它们对肝纤维化分期的影响是不同的:虽然两种不同仪器的 2D-SWE 能够检测肝纤维化,但在 HCC 患者中却产生了不同的结果。这些差异主要出现在F4肝纤维化患者身上,而在健康成人或F0-F3肝纤维化患者身上则没有观察到。造成仪器之间差异的一个潜在因素可能是 ALT 水平。
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Comparison of Two-Dimensional Shear Wave Elastography Between Two Different Instruments for Hepatocellular Carcinoma Patients.

Objectives: This study aimed to investigate and compare 2-dimensional shear wave elastography (2D-SWE) measurements and influencing factors among 2 different devices and to evaluate the ability and influencing factors of these measurements to assess liver fibrosis.

Methods: From October 2022 to September 2023, 290 hepatocellular carcinoma (HCC) patients and 30 healthy volunteers were prospectively included. The 2D-SWE measurements were performed using AixPlorer V (SEmean) and APLIO i900 (CEmean). This study compared 2D-SWE measurements between instruments for evaluating the liver fibrosis stage and analyzed the potential influencing factors.

Results: The 2D-SWE measurements obtained by the 2 instruments were significantly different (P < .001), but the differences were significant only for patients with stage F4 liver fibrosis (P < .001) and not for volunteers or patients with stage F0-F3 liver fibrosis (all P > .050). Multivariate linear regression analysis revealed that the factors independently influencing the SEmean were alanine aminotransferase (ALT) (P = .034) and liver fibrosis stage (P < .001), while fibrosis stage (P = .028) was the only factor influencing the CEmean.

Conclusions: Although 2D-SWE from the 2 different instruments was capable of detecting liver fibrosis, it yielded varying results in HCC patients. These discrepancies were predominantly observed in patients with F4 liver fibrosis but not in healthy adults or patients with F0-F3 liver fibrosis. One potential contributing factor to the differences between instruments could be ALT levels.

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来源期刊
CiteScore
5.10
自引率
4.30%
发文量
205
审稿时长
1.5 months
期刊介绍: The Journal of Ultrasound in Medicine (JUM) is dedicated to the rapid, accurate publication of original articles dealing with all aspects of medical ultrasound, particularly its direct application to patient care but also relevant basic science, advances in instrumentation, and biological effects. The journal is an official publication of the American Institute of Ultrasound in Medicine and publishes articles in a variety of categories, including Original Research papers, Review Articles, Pictorial Essays, Technical Innovations, Case Series, Letters to the Editor, and more, from an international bevy of countries in a continual effort to showcase and promote advances in the ultrasound community. Represented through these efforts are a wide variety of disciplines of ultrasound, including, but not limited to: -Basic Science- Breast Ultrasound- Contrast-Enhanced Ultrasound- Dermatology- Echocardiography- Elastography- Emergency Medicine- Fetal Echocardiography- Gastrointestinal Ultrasound- General and Abdominal Ultrasound- Genitourinary Ultrasound- Gynecologic Ultrasound- Head and Neck Ultrasound- High Frequency Clinical and Preclinical Imaging- Interventional-Intraoperative Ultrasound- Musculoskeletal Ultrasound- Neurosonology- Obstetric Ultrasound- Ophthalmologic Ultrasound- Pediatric Ultrasound- Point-of-Care Ultrasound- Public Policy- Superficial Structures- Therapeutic Ultrasound- Ultrasound Education- Ultrasound in Global Health- Urologic Ultrasound- Vascular Ultrasound
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