经尿道前列腺钬激光去核术与双极经尿道前列腺切除术治疗良性前列腺增生症的安全性和有效性:前瞻性随机对照试验。

IF 2.1 3区 医学 Q2 SURGERY Langenbeck's Archives of Surgery Pub Date : 2024-10-19 DOI:10.1007/s00423-024-03499-2
Bin Jiang, Ping Liang, Yanlei Wu, Wenmin Wang, Liping Shen
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引用次数: 0

摘要

目的:评估经尿道前列腺钬激光去核术(HoLEP)与双极经尿道前列腺切除术(bTUR-P)在治疗良性前列腺增生症(BPH)中的安全性和有效性:本研究共纳入了2022年1月至2023年9月期间住院的220名良性前列腺增生症患者。这些患者被随机分配到HoLEP组和bTUR-P组,每组110人。我们收集了两组患者的术前一般信息、围手术期数据、并发症和术后随访指标:结果:两组患者的基线特征相似,无统计学意义(P>0.05)。与 bTUR-P 组相比,HoLEP 组的术中出血量明显较少(P 结论:HoLEP 组的术中出血量明显少于 bTUR-P 组:经过综合评估,HoLEP 在安全性和有效性方面均优于 bTUR-P。因此,HoLEP可能是治疗良性前列腺增生症的首选。
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Safety and efficacy of transurethral holmium laser enucleation of the prostate versus bipolar transurethral resection of the prostate in the treatment of benign prostatic hyperplasia: a prospective randomized controlled trial.

Purpose: To evaluate the safety and efficacy of transurethral holmium laser enucleation of the prostate (HoLEP) compared to bipolar transurethral resection of the prostate (bTUR-P) in the treatment of benign prostatic hyperplasia (BPH).

Methods: A total of 220 BPH patients hospitalized from January 2022 to September 2023 were included in this study. These patients were randomly assigned to HoLEP and bTUR-P groups, with 110 participants in each group. We collected preoperative general information, perioperative data, complications, and postoperative follow-up indicators from both groups of patients.

Results: The baseline characteristics of patients in both groups were similar, with no statistical significance (P > 0.05). Compared to the bTUR-P group, the HoLEP group exhibited significantly less intraoperative bleeding (P < 0.001), shorter bladder irrigation time (P = 0.002), shorter catheter retention time (P < 0.001), and reduced postoperative hospitalization (P = 0.002). Additionally, the pain score during urination after catheter removal was significantly lower in the HoLEP group (P < 0.001). Postoperative complications occurred in both groups; however, they were less frequent in the HoLEP group (4 cases), primarily consisting of urinary retention and postoperative bleeding. The bTUR-P group experienced more complications (9 cases). Significant reductions in postoperative residual urine volume (RUV) were observed in both groups (P < 0.001). Both groups also showed significant improvements in Quality of Life (QoL) scores and International Prostate Symptom Scores (IPSS), with the HoLEP group demonstrating a more significant decrease in IPSS (P < 0.001).

Conclusion: After comprehensive evaluation, HoLEP was superior to bTUR-P in terms of safety and efficacy. Therefore, HoLEP may be a preferable choice for the treatment of BPH.

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来源期刊
CiteScore
3.30
自引率
8.70%
发文量
342
审稿时长
4-8 weeks
期刊介绍: Langenbeck''s Archives of Surgery aims to publish the best results in the field of clinical surgery and basic surgical research. The main focus is on providing the highest level of clinical research and clinically relevant basic research. The journal, published exclusively in English, will provide an international discussion forum for the controlled results of clinical surgery. The majority of published contributions will be original articles reporting on clinical data from general and visceral surgery, while endocrine surgery will also be covered. Papers on basic surgical principles from the fields of traumatology, vascular and thoracic surgery are also welcome. Evidence-based medicine is an important criterion for the acceptance of papers.
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