成功进行乙状结肠腹腔镜分离术后早期复发的处理方法。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-10-01 DOI:10.12669/pjms.40.9.10078
Nurhak Aksungur, Esra Disci, Rifat Peksoz, Sabri Selcuk Atamanalp
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引用次数: 0

摘要

目的:内镜下分离术后,3%-86%的患者会复发乙状结肠肿(SV),其中约13%是在首次入院期间出现的早期复发。虽然半选择性手术是传统方法,但在重复内镜检查或经皮内镜乙状结肠吻合术(PES)后进行选择性手术也是治疗早期 SV 复发的其他方法。我们的目的是讨论半选择性手术在上述罕见临床实体中的作用:在我们的 1,076 例系列病例中,我们回顾性评估了在 1966 年 6 月至 1986 年 6 月期间接受治疗的 612 例患者(56.9%)的记录,并前瞻性地利用了在 1986 年 6 月至 2024 年 1 月期间接受治疗的 464 例患者(43.1%)的数据。我们记录了每位患者的治疗方案和预后:结果:在成功进行非手术分离的 621 例患者中,有 34 例(5.5%)确定为 SV 早期复发。我们对所有这些患者进行了半选择性手术治疗。手术方法包括:1 名患者(2.9%)的分离术、11 名患者(32.4%)的中层吻合术、17 名患者(50.0%)的乙状结肠切除术和 5 名患者(14.7%)的乙状结肠造口术。该系列手术的死亡率和发病率分别为 2.9%(1 例患者)和 14.7%(5 例患者):半选择性手术是大多数外科医生尝试的传统方法,可使患者恢复一般状态、肠道准备和抗生素预防。然而,对于一些经过挑选的患者,目前的替代方法是重复内窥镜检查,然后进行选择性手术或 PES。遗憾的是,重复性内窥镜剥离术成功后,择期手术的有效率相对较低,而且复发导致的预后不良仍是后一种手术的重要缺陷。
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Management of early recurrence following successful endoscopic detorsion in sigmoid volvulus.

Objectives: Following endoscopic detorsion, sigmoid volvulus (SV) recurs in 3%-86% of patients, approximately 13% of which are early recurrence presenting during the first admission period. Although semielective surgery is the traditional approach, elective surgery following repetitive endoscopy or percutaneous endoscopic sigmoidopexy (PES) are other alternatives in the management of early SV recurrence. Our aim was to discuss the role of semielective surgery in above-mentioned rare clinical entity.

Methods: Among our 1,076-case series, we retrospectively evaluated the records of 612 patients (56.9%) treated between June 1966 and June 1986, while we prospectively utilized the data of 464 patients (43.1%) managed between June 1986 and January 2024. We recorded the treatment option and prognosis for each patient.

Results: Early SV recurrence was determined in 34 (5.5%) of the 621 patients with successful nonoperative detorsion. We treated all of these patients by semielective surgery. The surgical procedures were detorsion in one patient (2.9%), mesopexy in 11 (32.4%), sigmoidectomy with primary anastomosis in 17 (50.0%), and sigmoidectomy with stoma in five (14.7%). In this series, mortality and morbidity rates were 2.9% (one patient) and 14.7% (five patients), respectively.

Conclusion: Semielective surgery is the traditional approach tried by most surgeons, which allows for the recovery of the general status of the patients, bowel preparation, and antibiotic prophylaxis. However, repetitive endoscopy followed by elective surgery or PES are current alternatives for some selected patients. Unfortunately, the relatively low effectuation rate of elective surgery following successful repetitive endoscopic detorsion and recurrence-related poor prognosis are still important handicaps of the latter procedure.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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