IPEM 专题报告:英国首次对成年患者放疗验证成像中锥束 CT 剂量指数的调查。

IF 3.3 3区 医学 Q2 ENGINEERING, BIOMEDICAL Physics in medicine and biology Pub Date : 2024-11-06 DOI:10.1088/1361-6560/ad88d1
Tim J Wood, Anne T Davis, James Earley, Sue Edyvean, Una Findlay, Rebecca Lindsay, Rosaleen Plaistow, Matthew Williams
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引用次数: 0

摘要

锥形束 CT 是大多数现代放射治疗不可或缺的组成部分。每天重复进行 CBCT 成像会导致大量组织的成像剂量增大,甚至超出治疗部位。因此,在确保图像适合临床任务的同时,还必须确保对曝光进行优化,以保持尽可能低的剂量。 这份 IPEM 专题报告介绍了英国首次对 CBCT 放射治疗中的剂量指数进行调查的结果。我们收集了锥形束剂量指数(CBDIw)所定义的剂量测量值以及七个治疗点的方案信息。如果某中心有一系列优化方案,则要求提供患者数据样本,以证明方案使用的差异。根据每种直线加速器的平均剂量测定数据确定方案 CBDIw 值,并计算出每个中心每个治疗点的 CBDIw 中位数和扫描长度。对 CBDIw 中位值进行比较,并得出汇总统计数据,以便制定国家剂量参考水平 (DRL)。建议的 CBDIw DRL 为:前列腺 20.6 mGy、妇科 20.8 mGy、乳腺 5.0 mGy、3D 肺 6.0 mGy、4D 肺 11.8 mGy、脑 3.5 mGy 和头颈部 4.2 mGy。然而,不同型号的成像系统之间存在很大差异。如果中心采取了积极的优化策略,例如基于尺寸的方案,并制定了选择标准,那么与供应商的默认值相比,"普通 "患者的剂量就有可能降低。一些临床中心对扫描长度进行了优化,Elekta 用户倾向于为前列腺成像(相对较短)和妇科治疗(最长)安装不同的准直器。这与大多数瓦里安用户在大多数情况下使用默认扫描长度形成鲜明对比。
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IPEM topical report: the first UK survey of cone beam CT dose indices in radiotherapy verification imaging for adult patients.

Cone beam CT is integral to most modern radiotherapy treatments. The application of daily and repeat CBCT imaging can lead to high imaging doses over a large volume of tissue that extends beyond the treatment site. Hence, it is important to ensure exposures are optimised to keep doses as low as reasonably achievable, whilst ensuring images are suitable for the clinical task. This IPEM topical report presents the results of the first UK survey of dose indices in radiotherapy CBCT. Dose measurements, as defined by the cone beam dose index (CBDIw), were collected along with protocol information for seven treatment sites. Where a range of optimised protocols were available in a centre, a sample of patient data demonstrating the variation in protocol use were requested. Protocol CBDIwvalues were determined from the average dosimetry data for each type of linear accelerator, and median CBDIwand scan length were calculated for each treatment site at each centre. Median CBDIwvalues were compared and summary statistics derived that enable the setting of national dose reference levels (DRLs). A total of 63 UK radiotherapy centres contributed data. The proposed CBDIwDRLs are; prostate 20.6 mGy, gynaecological 20.8 mGy, breast 5.0 mGy, 3D-lung 6.0 mGy, 4D-lung 11.8 mGy, brain 3.5 mGy and head/neck 4.2 mGy. However, large differences between models of imaging system were noted. Where centres had pro-active optimisation strategies in place, such as sized based protocols with selection criteria, dose reductions on the 'average' patient were possible compared with vendor defaults. Optimisation of scan length was noted in some clinical sites, with Elekta users tending to fit different collimators for prostate imaging (relatively short) compared with gynaecological treatments (longest). This contrasts with most Varian users who apply the default scan length in most cases.

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来源期刊
Physics in medicine and biology
Physics in medicine and biology 医学-工程:生物医学
CiteScore
6.50
自引率
14.30%
发文量
409
审稿时长
2 months
期刊介绍: The development and application of theoretical, computational and experimental physics to medicine, physiology and biology. Topics covered are: therapy physics (including ionizing and non-ionizing radiation); biomedical imaging (e.g. x-ray, magnetic resonance, ultrasound, optical and nuclear imaging); image-guided interventions; image reconstruction and analysis (including kinetic modelling); artificial intelligence in biomedical physics and analysis; nanoparticles in imaging and therapy; radiobiology; radiation protection and patient dose monitoring; radiation dosimetry
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