揭示基于蛋白质的可持续抗菌材料的潜力。

IF 4.4 2区 生物学 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY Probiotics and Antimicrobial Proteins Pub Date : 2024-10-18 DOI:10.1007/s12602-024-10381-6
Iqra Ghouri, Muslum Demir, Shahid Ali Khan, Muhammad Adil Mansoor, Mudassir Iqbal
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引用次数: 0

摘要

细菌数量激增,对多种抗生素药物的耐药性不断升级,已成为一个令人担忧的全球性威胁,需要采取紧急和创新的干预措施。为了应对这一危险,科学家们已着手开发先进的生物相容性抗菌材料,目的不仅是为了应对细菌感染,还为了应对微生物繁殖导致的食品腐败这一普遍问题。以蛋白质为基础的生物聚合物及其精心设计的复合材料正处于这一领域的前沿。它们在解决这一全球关注的严重问题方面的潜力提供了一种生物医学和环境科学领域交叉的方法。本综述文章深入探讨了从天然来源中提取各种蛋白质所采用的复杂提取工艺,揭示了支撑其抗菌特性的复杂生化途径。在基础知识的基础上,这篇综述还对功能化蛋白质进行了全面综合,对其进行修饰以增强其抗菌功效,从而为特定的生物医学和环境应用提供量身定制的解决方案。本综述介绍了这些材料的抗菌应用;从伤口敷料到具有固有抗菌特性的包装材料,其潜在应用凸显了这些材料的多功能性和适应性。此外,本综述还是一份宝贵的路线图,可指导未来的研究工作,在全球范围内重塑天然抗菌材料的面貌。
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Unveiling the Potential of Protein-Based Sustainable Antibacterial Materials.

The surge in bacterial growth and the escalating resistance against a multitude of antibiotic drugs have burgeoned into an alarming global threat, necessitating urgent and innovative interventions. In response to this peril, scientists have embarked on the development of advanced biocompatible antibacterial materials, aiming to counteract not only bacterial infections but also the pervasive issue of food spoilage resulting from microbial proliferation. Protein-based biopolymers and their meticulously engineered composites are at the forefront of this endeavor. Their potential in combating this severe global concern presents an approach that intersects the domains of biomedicine and environmental science. The present review article delves into the intricate extraction processes employed to derive various proteins from their natural sources, unraveling the complex biochemical pathways that underpin their antibacterial properties. Expanding on the foundational knowledge, the review also provides a comprehensive synthesis of functionalized proteins modified to enhance their antibacterial efficacy, unveiling a realm of possibilities for tailoring solutions to specific biomedical and environmental applications. The present review navigates through their antibacterial applications; from wound dressings to packaging materials with inherent antibacterial properties, the potential applications underscore the versatility and adaptability of these materials. Moreover, this comprehensive review serves as a valuable roadmap, guiding future research endeavors in reshaping the landscape of natural antibacterial materials on a global scale.

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来源期刊
Probiotics and Antimicrobial Proteins
Probiotics and Antimicrobial Proteins BIOTECHNOLOGY & APPLIED MICROBIOLOGYMICROB-MICROBIOLOGY
CiteScore
11.30
自引率
6.10%
发文量
140
期刊介绍: Probiotics and Antimicrobial Proteins publishes reviews, original articles, letters and short notes and technical/methodological communications aimed at advancing fundamental knowledge and exploration of the applications of probiotics, natural antimicrobial proteins and their derivatives in biomedical, agricultural, veterinary, food, and cosmetic products. The Journal welcomes fundamental research articles and reports on applications of these microorganisms and substances, and encourages structural studies and studies that correlate the structure and functional properties of antimicrobial proteins.
期刊最新文献
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