开发马子宫内膜组织学评分系统，以补充 Kenney-Doig 量表。

IF 1.6 3区农林科学 Q2 AGRICULTURE, DAIRY & ANIMAL SCIENCE Reproduction in Domestic Animals Pub Date : 2024-10-01 DOI:10.1111/rda.14614

I Martínez-Bartolomé, J Masot, C Serres

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引用次数: 0

摘要

肯尼-多依格评分法被认为是对母马子宫活组织检查进行分类的国际标准方法，但其客观性受到了多项研究的质疑。在本研究中，我们分析了两名病理学家在评估同一组 201 例子宫活检组织时的一致程度，结果显示一致程度为轻微至中等（κ = .34/κw = .57）。随后，我们根据炎症、纤维化、腺体密度和淋巴管腔等组织学参数的评估结果制定了一个数字量表。部分分数相加得出第五个参数，称为总和。两个量表之间存在相关性（p w = .67）。

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Development of an equine endometrial histology scoring system to complement the Kenney-Doig scale.

Kenney-Doig scale is considered the international standard method for classifying uterine biopsies in mares; however, its objectivity has been questioned by various studies. In the present study, we analysed the degree of agreement between two pathologists when assessing the same set of 201 uterine biopsies, obtaining a slight to moderate level of agreement (κ = .34/κ_w = .57). Subsequently, we developed a numerical scale based on the evaluation of histological parameters, including inflammation, fibrosis, glandular density and lymphatic lacunae. Partial scores were summed to obtain a fifth parameter called Summation. The correlation between both scales was demonstrated (p < .0001), and their combined use resulted in a notable increase in the degree of agreement between the two pathologists (κ = .53/κ_w = .67).

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来源期刊

Reproduction in Domestic Animals 农林科学-奶制品与动物科学

CiteScore

3.00

自引率

5.90%

发文量

238

审稿时长

4-8 weeks

期刊介绍： The journal offers comprehensive information concerning physiology, pathology, and biotechnology of reproduction. Topical results are currently published in original papers, reviews, and short communications with particular attention to investigations on practicable techniques. Carefully selected reports, e. g. on embryo transfer and associated biotechnologies, gene transfer, and spermatology provide a link between basic research and clinical application. The journal applies to breeders, veterinarians, and biologists, and is also of interest in human medicine. Interdisciplinary cooperation is documented in the proceedings of the joint annual meetings. Fields of interest: Animal reproduction and biotechnology with special regard to investigations on applied and clinical research.