前交叉韧带重建术后开放结构生物复合干扰螺钉的吸收特性。

IF 2 Q2 ORTHOPEDICS Journal of Experimental Orthopaedics Pub Date : 2024-10-21 DOI:10.1002/jeo2.70016

Martin Lind, Torsten Grønbech Nielsen, Flemming K. Nielsen, Ole G. Sørensen, Bjarne Mygind-Klavsen, Peter Faunø

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引用次数: 0

摘要

目的：用于前交叉韧带重建（ACLR）的可吸收干扰螺钉可能导致隧道增宽和囊肿形成。Biosure Regenesorb 干扰螺钉（Smith & Nephew）采用优化的磷酸钙/聚合物成分，可在吸收过程中促进骨形成。本研究旨在调查使用 Biosure Regenesorb 螺钉胫骨固定进行 ACLR 后的螺钉吸收、新骨形成和隧道几何形状：本研究是一项前瞻性单中心病例系列研究，共收集了 12 例前交叉韧带损伤患者的病例，采用腘绳肌腱自体移植和 Biosure Regenesorb 干扰螺钉胫骨固定进行前交叉韧带重建治疗，随访两年。Biosure Regenesorb 由 65% 的聚乳酸-乙醇酸聚酯、20% 的硫酸钙和 15% 的聚丙烯组成。20% 的硫酸钙和 15% 的磷酸三钙。主要终点通过定量计算机断层扫描（CT）评估隧道体积、植入物体积和胫骨隧道内新骨形成情况。次要终点：关节测量膝关节松弛度、国际膝关节文献委员会（IKDC）和膝关节骨关节炎与损伤结果评分（KOOS）以及 Tegner 活动量表：结果：在两年的随访期内，螺钉量减少了44%，而隧道量保持不变。结果：在两年的随访期内，螺钉体积减少了 44%，而隧道体积保持不变：使用 Biosure Regenesorb 干扰螺钉进行 ACLR 不会导致隧道增宽，两年后螺钉吸收了 44%，只有少量新骨形成。膝关节稳定性和主观结果的改善与其他 ACLR 方法的预期相同：证据等级：IV。

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Resorption characteristics of an open architecture biocomposite interference screw after ACL reconstruction

Purpose

Absorbable interference screws for anterior cruciate ligament reconstruction (ACLR) can lead to tunnel widening and cyst formation. The Biosure Regenesorb interference screw (Smith & Nephew). has been developed with an optimised calcium phosphate/polymer composition to promote bone formation during resorption. The present study aims to investigate screw resorption, new bone formation, and tunnel geometry following ACLR with Biosure Regenesorb screw tibial fixation.

Methods

The study is a prospective single-centre case series of 12 patients with ACL lesions and treated with ACLR using hamstring tendon autograft with Biosure Regenesorb interference screw tibial fixation with a two-year follow-up period. The Biosure Regenesorb consists of 65% polylactide-glycolic acid poly. 20% calcium sulphate and 15% tricalcium phosphate. Primary endpoint: Tunnel volume. implant volume and new bone formation in the tibial tunnel is evaluated by quantitative computed tomography (CT) scanning. Secondary endpoints: Arthrometric knee laxity, International Knee Documentation Committee (IKDC) and Knee Osteoarthritis and Injury Outcome Scores (KOOS) and Tegner activity scale.

Results

Screw volume decreased to 44% within the two-year follow-up period while tunnel volume remained unchanged. Only a minor amount (<1% of tunnel volume) of new bone formation in the screw remnants was observed. Sagittal knee laxity at one year was 0.9 mm. The IKDC score increased by 15 points and the KOOS sport and KOOS quality of life scores increased by 25 and 26 points. respectively.

Conclusion

ACLR using Biosure Regenesorb interference screw does not result in tunnel widening. showing a screw resorption of 44% after two years and minor new bone formation. Knee stability and subjective outcome improvements are as expected after other ACLR methods.