肝血管肌脂肪瘤的对比增强超声特征:与 AFP 阴性和非病毒性肝细胞癌的比较。

IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Ultrasound International Open Pub Date : 2024-06-14 eCollection Date: 2024-01-01 DOI:10.1055/a-2318-6654
Yafang Zhang, Zhi-Xing Guo, Ying Liao, Yiwen Yu, Ruohan Guo, Xu Han, Lilong Lan, Jianhua Zhou
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引用次数: 0

摘要

目的 本研究旨在比较对比增强超声(CEUS)检查肝血管脂肪瘤(HAML)和具有挑战性的 HCC 病例(主要是那些没有肝炎感染但 AFP 水平较低的病例(非病毒性 AFP- HCC))的特征。材料与方法 该研究纳入了 2012 年至 2023 年期间接受 CEUS 检查并经病理证实的 HAML 和非病毒性 AFP- HCC。比较两组患者的Sonovue(SV)CEUS和Sonazoid(SZ)CEUS特征。结果 研究包括50例HAML(SZ-CEUS为24%)和88例非病毒性AFP- HCC(SZ-CEUS为21.6%)。SZ-CEUS 的 CEUS 特征在一定程度上与 SV-CEUS 相似。在晚期和血管后阶段,HAML更常表现为无冲洗和部分冲洗与部分无冲洗,即所谓的PWNW,而HCC则更常表现为轻度冲洗。在血管后阶段,所有非病毒 AFP- HCC 都表现出冲洗,从而有助于与无冲洗 HAML 区分开来,而在 SV-CEUS 中,一些非病毒 AFP- HCC 在晚期阶段仍表现出无冲洗,无法与 HAML 区分开来。值得注意的是,PWNW 只出现在结节出现高回声和低回声分离的结节中,而在 SZ-CEUS 上,HAML 在血管后阶段的高回声和低回声分离比晚期阶段更频繁地表现出 PWNW,这可能有助于将出现高回声和低回声分离的结节区分为 HAML 或非病毒 AFP- HCC。结论本研究强调了 SV- 和 SZ-CEUS 在区分 HAML 和非病毒 AFP- HCC 方面的作用,并填补了有关 HAML SZ-CEUS 特征的现有空白。
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Contrast-enhanced ultrasound features of hepatic angiomyolipoma: comparison with AFP-negative and non-viral hepatocellular carcinoma.

Purpose  This study aimed to compare contrast-enhanced ultrasound (CEUS) features of hepatic angiomyolipoma (HAML) and challenging cases of HCC, mainly those with no hepatitis infection but also with a low level of AFP (non-viral AFP- HCC). Materials and Methods  The study included pathologically confirmed HAMLs and non-viral AFP- HCCs undergoing CEUS from 2012 to 2023. Sonovue (SV) CEUS and Sonazoid (SZ) CEUS characteristics of the two groups were compared. Results  The study included 50 HAMLs (24% on SZ-CEUS) and 88 non-viral AFP- HCCs (21.6% on SZ-CEUS). The CEUS characteristics on SZ-CEUS were similar to those on SV-CEUS to a certain extent. HAMLs more frequently displayed no washout and partial washout with partial no washout, so-called PWNW, in the late phase and post-vascular phase, whereas HCCs more commonly exhibited mild washout. In the post-vascular phase, all non-viral AFP- HCCs exhibited washout, thereby facilitating differentiation from no-washoutHAMLs, superior to SV-CEUS, where some non-viral AFP- HCCs still exhibited no washout in late phase that could not be distinguished from HAMLs. It is noteworthy that PWNW was exclusively found in nodules exhibiting hyper- and hypoechoic separation of the nodules, and hyper- and hypoechoic separation of HAMLs in the post-vascular phase on SZ-CEUS demonstrated PWNW more frequently compared to the late phase, which can potentially help distinguish nodules with hyper- and hypoechoic separation as either HAML or non-viral AFP- HCC. Conclusion: This study highlighted the usefulness of SV- and SZ-CEUS for distinguishing HAML and non-viral AFP- HCC and filled in existing gaps regarding the SZ-CEUS features of HAML.

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来源期刊
Ultrasound International Open
Ultrasound International Open RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
3.00
自引率
0.00%
发文量
7
审稿时长
12 weeks
期刊最新文献
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