带有叠加尖峰的节律性高振幅三角洲（RHADS）：治疗难题。

IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL Oxford Medical Case Reports Pub Date : 2024-10-15 eCollection Date: 2024-10-01 DOI:10.1093/omcr/omae114

Vanita Shukla, Paul Webb, Bashayer AlMohaimeed, James Lee, Cyrus Boelman

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引用次数: 0

摘要

在安杰尔曼综合征和雷特综合征等遗传性疾病中，已经描述了具有病理特征的脑电图模式。随着连续脑电图监测技术的普及，发作期-发作间期连续的脑电图模式已被越来越多的人所认识；然而，治疗决策可能很难做出，对临床的影响也难以预料。有节奏的高幅三角活动与叠加（多）尖峰（RHADS）被描述为 POLG1 Alpers 综合征的一种特殊脑电图模式。如何在治疗亚临床癫痫发作和控制这些患者的脑病之间取得平衡是一项挑战。

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Rhythmic high-amplitude delta with superimposed spikes (RHADS): a treatment dilemma.

Pathognomonic EEG patterns have been described in genetic conditions such as Angelman and Rett syndromes. EEG patterns along the ictal-interictal continuum have been increasingly recognized with the greater availability of continuous EEG monitoring; however, treatment decisions may be difficult with unpredictable clinical implications. Rhythmic High-Amplitude Delta Activity with Superimposed (Poly) Spikes (RHADS) has been described as a particular EEG pattern in POLG1 Alpers Syndrome. The balance between treating subclinical seizures and managing encephalopathy in these patients is challenging.

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来源期刊

Oxford Medical Case Reports MEDICINE, GENERAL & INTERNAL-

CiteScore

0.90

自引率

0.00%

发文量

125

审稿时长

19 weeks

期刊介绍： Oxford Medical Case Reports (OMCR) is an open access, peer-reviewed online journal publishing original and educationally valuable case reports that expand the field of medicine. The journal covers all medical specialities including cardiology, rheumatology, nephrology, oncology, neurology, and reproduction, comprising a comprehensive resource for physicians in all fields and at all stages of training. Oxford Medical Case Reports deposits all articles in PubMed Central (PMC). Physicians and researchers can find your work through PubMed , helping you reach the widest possible audience. The journal is also indexed in the Web of Science Core Collection . Oxford Medical Case Reports publishes case reports under the following categories: Allergy Audiovestibular medicine Cardiology and cardiovascular systems Critical care medicine Dermatology Emergency medicine Endocrinology and metabolism Gastroenterology and hepatology Geriatrics and gerontology Haematology Immunology Infectious diseases and tropical medicine Medical disorders in pregnancy Medical ophthalmology Nephrology Neurology Oncology Paediatrics Pain Palliative medicine Pharmacology and pharmacy Psychiatry Radiology, nuclear medicine, and medical imaging Respiratory disorders Rheumatology Sexual and reproductive health Sports Medicine Substance abuse.