Maria-Consuelo Pintado, Ana Oñoro, Diego Beltran, Emilio Nevado
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They had higher severity scores at ICU admission. 1 patient required initiation of invasive mechanical ventilation during ICU admission due to pneumonia, and 1 patient needed placement of a pleural chest tube due to symptomatic pleural effusion.Only the need for a high fluid balance during surgery was correlated to the development of respiratory complications on multivariate analysis.Median ICU stay was 5 (4.0-5.0) days. ICU mortality was 0.8.0%.</p><p><strong>Conclusion: </strong>In our study, 54% of patients treated with CRS and HIPEC developed respiratory complications during the postoperative period. However, the majority of these complications were not severe and did not significantly impact mortality rates or hospital stays.</p><p><strong>How to cite this article: </strong>Pintado MC, Oñoro A, Beltran D, Nevado E. Respiratory Complications in the Immediate Postoperative Period after Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy Nowadays: An Observational Study. Indian J Crit Care Med 2024;28(10):952-957.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":null,"pages":null},"PeriodicalIF":1.5000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11471978/pdf/","citationCount":"0","resultStr":"{\"title\":\"Respiratory Complications in the Immediate Postoperative Period after Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy Nowadays: An Observational Study.\",\"authors\":\"Maria-Consuelo Pintado, Ana Oñoro, Diego Beltran, Emilio Nevado\",\"doi\":\"10.5005/jp-journals-10071-24810\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background and objectives: </strong>Several respiratory complications have been described after cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC).</p><p><strong>Materials and methods: </strong>Patients admitted to intensive care unit (ICU) after CRS and HIPEC during 10 years.</p><p><strong>Data recorded were: </strong>Demographic characteristics; severity of illness; complete blood sample; chest radiographs; type of cancer and extension; HIPEC drug and temperature; ICU and hospital stay; and mortality.</p><p><strong>Results: </strong>Of the 124 patients included, 67 patients (54.0%) presented respiratory complications: 56 (83.6%) acute respiratory failure, 25 (37.3%) pleural effusion, 13 (19.4%) atelectasis, and 3 (4.5%) other; only 1 (3.0%) developed pneumonia. They had higher severity scores at ICU admission. 1 patient required initiation of invasive mechanical ventilation during ICU admission due to pneumonia, and 1 patient needed placement of a pleural chest tube due to symptomatic pleural effusion.Only the need for a high fluid balance during surgery was correlated to the development of respiratory complications on multivariate analysis.Median ICU stay was 5 (4.0-5.0) days. ICU mortality was 0.8.0%.</p><p><strong>Conclusion: </strong>In our study, 54% of patients treated with CRS and HIPEC developed respiratory complications during the postoperative period. However, the majority of these complications were not severe and did not significantly impact mortality rates or hospital stays.</p><p><strong>How to cite this article: </strong>Pintado MC, Oñoro A, Beltran D, Nevado E. Respiratory Complications in the Immediate Postoperative Period after Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy Nowadays: An Observational Study. 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引用次数: 0
摘要
背景和目的:材料和方法:10年间,接受过CRS和腹腔内热化疗(HIPEC)的患者入住重症监护室(ICU):10 年间接受过 CRS 和 HIPEC 后入住重症监护室(ICU)的患者:记录的数据包括:人口统计学特征、病情严重程度、全血样本、胸片、癌症类型和扩展、HIPEC药物和温度、重症监护室和住院时间以及死亡率:在纳入的124名患者中,67名患者(54.0%)出现呼吸系统并发症:56人(83.6%)出现急性呼吸衰竭,25人(37.3%)出现胸腔积液,13人(19.4%)出现肺不张,3人(4.5%)出现其他并发症;只有1人(3.0%)出现肺炎。他们在入住重症监护室时的严重程度评分较高。在多变量分析中,只有手术期间需要高液体平衡与呼吸系统并发症的发生相关。ICU死亡率为0.8.0%:在我们的研究中,54%接受CRS和HIPEC治疗的患者在术后出现了呼吸系统并发症。然而,这些并发症大多并不严重,对死亡率或住院时间没有显著影响:Pintado MC、Oñoro A、Beltran D、Nevado E.如今的细胞减灭术和腹腔内热化疗术后即刻出现的呼吸道并发症:一项观察性研究。Indian J Crit Care Med 2024;28(10):952-957.
Respiratory Complications in the Immediate Postoperative Period after Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy Nowadays: An Observational Study.
Background and objectives: Several respiratory complications have been described after cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC).
Materials and methods: Patients admitted to intensive care unit (ICU) after CRS and HIPEC during 10 years.
Data recorded were: Demographic characteristics; severity of illness; complete blood sample; chest radiographs; type of cancer and extension; HIPEC drug and temperature; ICU and hospital stay; and mortality.
Results: Of the 124 patients included, 67 patients (54.0%) presented respiratory complications: 56 (83.6%) acute respiratory failure, 25 (37.3%) pleural effusion, 13 (19.4%) atelectasis, and 3 (4.5%) other; only 1 (3.0%) developed pneumonia. They had higher severity scores at ICU admission. 1 patient required initiation of invasive mechanical ventilation during ICU admission due to pneumonia, and 1 patient needed placement of a pleural chest tube due to symptomatic pleural effusion.Only the need for a high fluid balance during surgery was correlated to the development of respiratory complications on multivariate analysis.Median ICU stay was 5 (4.0-5.0) days. ICU mortality was 0.8.0%.
Conclusion: In our study, 54% of patients treated with CRS and HIPEC developed respiratory complications during the postoperative period. However, the majority of these complications were not severe and did not significantly impact mortality rates or hospital stays.
How to cite this article: Pintado MC, Oñoro A, Beltran D, Nevado E. Respiratory Complications in the Immediate Postoperative Period after Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy Nowadays: An Observational Study. Indian J Crit Care Med 2024;28(10):952-957.
期刊介绍:
Indian Journal of Critical Care Medicine (ISSN 0972-5229) is specialty periodical published under the auspices of Indian Society of Critical Care Medicine. Journal encourages research, education and dissemination of knowledge in the fields of critical and emergency medicine.