Christina S Hwang, Martha P Montgomery, Diana I Diaz Munoz, Shaoman Yin, Eyasu H Teshale, Angelica Bocour
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Validation of a Simplified Laboratory-Based HCV Clearance Definition Using New York City Hepatitis C Program and Surveillance Data.
Context: Laboratory-based hepatitis C virus (HCV) clearance cascades are an important tool for health departments to track progress toward HCV elimination, but a laboratory-based definition of HCV clearance has not yet been validated.
Objective: To compare agreement between a laboratory-based HCV clearance definition with a clinical cure definition.
Design: Observational.
Setting: New York City Department of Health and Mental Hygiene HCV surveillance system data and New York City hepatitis C linkage-to-care program data.
Participants: Linkage-to-care program participants who were diagnosed with hepatitis C and enrolled in the linkage-to-care program from July 1, 2016, through June 30, 2020.
Main outcome measure: Percent agreement between a laboratory-based HCV clearance definition (surveillance system) and a clinical cure definition (program data).
Results: Among 591 program participants with known treatment outcome, the laboratory-based HCV clearance definition and clinical cure definition were concordant in 573 cases (97%).
Conclusions: A laboratory-based HCV clearance definition based on public health surveillance data can be a reliable source for monitoring HCV elimination.
期刊介绍：
Journal of Public Health Management and Practice publishes articles which focus on evidence based public health practice and research. The journal is a bi-monthly peer-reviewed publication guided by a multidisciplinary editorial board of administrators, practitioners and scientists. Journal of Public Health Management and Practice publishes in a wide range of population health topics including research to practice; emergency preparedness; bioterrorism; infectious disease surveillance; environmental health; community health assessment, chronic disease prevention and health promotion, and academic-practice linkages.
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