一些纤维蛋白溶解抑制剂和激活剂对大分子经毛细血管转运的影响。

Physiologie (Bucarest) Pub Date : 1987-07-01
F Don, L Grosu, T Pavel, M Cucuianu, M Grigercsik, I Baciu
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引用次数: 0

摘要

在抑制和激活纤维蛋白溶解的物质(分别为Trasylol、EACA、Streptokinase和Salyrgan)的影响下,对11只经氯氯蔗糖麻醉和腘窝淋巴管插管的狗后爪的RISA经毛细血管转运进行了随访。发现EACA抑制了RISA的经毛细血管转运,而链激酶激活了它。Trasylol和Salyrgan没有产生变化,示踪剂消失曲线的斜率与对照组相同。
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Influence of some inhibitors and activators of fibrinolysis on transcapillary transport of macromolecules.

The RISA transcapillary transport in the posterior paw was followed up under the influence of some substances inhibiting and activating fibrinolysis (Trasylol, EACA and Streptokinase and Salyrgan, respectively) in 11 dogs under narcosis with chloralose and the cannulation of the lymphatics in the popliteal space. It was found that EACA inhibits the transcapillary RISA transport and streptokinase activates it. Trasylol and Salyrgan produced no changes, the slope of the vanishing curve of the tracer being identical with that of the controls.

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