Lihong Chen, Ning Pan, Bin Hu, Yaofeng Li, Shushan Dong, Yinan Zhou, Jianxin Guo, Jian Yang, Yongbai Luo, Zhijie Jian
{"title":"使用 8 厘米双层探测器光谱计算机断层扫描观察冠状动脉支架的单能重建和碘密度图:体外模型研究。","authors":"Lihong Chen, Ning Pan, Bin Hu, Yaofeng Li, Shushan Dong, Yinan Zhou, Jianxin Guo, Jian Yang, Yongbai Luo, Zhijie Jian","doi":"10.21037/qims-24-786","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>The effectiveness of coronary computed tomography (CT) angiography in assessing stent restenosis is hindered by heavy metal artifacts. This study aimed to evaluate the image quality of monoenergetic reconstructions and iodine density map for coronary stent imaging using an 8-cm dual-layer detector spectral CT.</p><p><strong>Methods: </strong>In this study, 8 stents with a diameter <3 mm (group A) and 10 with a diameter ≥3 mm (group B) were placed in plastic tubes filled with iodinated contrast media and scanned. The internal diameter of the prepared stents was then measured by intravascular ultrasound. The reconstructed images included iodine density maps, conventional images, and different energy levels. The visualization of the stent lumen and stent structure was subjectively assessed using a 4-point Likert scale. The objective evaluation was performed using the in-stent lumen signal-to-noise ratio (SNRis), non-stent lumen SNR (SNRns), internal diameter difference (IDD), and blooming artifact index (BAI). The Friedman test and analysis of variance were used for multiple comparisons.</p><p><strong>Results: </strong>For lumen visualization, the optimal monoenergetic images received the highest score for both group A (2.56±0.51) and group B (3.1±0.55). Multiple comparisons showed that there were significant differences between the optimal monoenergetic images and iodine density maps. However, for stent structure, iodine density maps received the highest score for group A (3.0±0.52) and group B (3.8±0.41). For quantitative assessment, the optimal monoenergetic images had the highest SNRis and SNRns, while the iodine density maps had the lowest SNRis and SNRns. For IDD and BAI, the iodine density maps yielded the smallest value.</p><p><strong>Conclusions: </strong>The monoenergetic images on the second-generation dual-layer detector CT provide better visualization of the lumen and higher SNR. However, iodine density maps are superior for evaluating stent structure and IDD and BAI compared to monoenergetic and conventional reconstructions.</p>","PeriodicalId":54267,"journal":{"name":"Quantitative Imaging in Medicine and Surgery","volume":null,"pages":null},"PeriodicalIF":2.9000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11485354/pdf/","citationCount":"0","resultStr":"{\"title\":\"Monoenergetic reconstructions and iodine density maps for visualization of coronary artery stents using 8-cm dual-layer detector spectral computed tomography: an <i>in vitro</i> phantom study.\",\"authors\":\"Lihong Chen, Ning Pan, Bin Hu, Yaofeng Li, Shushan Dong, Yinan Zhou, Jianxin Guo, Jian Yang, Yongbai Luo, Zhijie Jian\",\"doi\":\"10.21037/qims-24-786\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>The effectiveness of coronary computed tomography (CT) angiography in assessing stent restenosis is hindered by heavy metal artifacts. This study aimed to evaluate the image quality of monoenergetic reconstructions and iodine density map for coronary stent imaging using an 8-cm dual-layer detector spectral CT.</p><p><strong>Methods: </strong>In this study, 8 stents with a diameter <3 mm (group A) and 10 with a diameter ≥3 mm (group B) were placed in plastic tubes filled with iodinated contrast media and scanned. The internal diameter of the prepared stents was then measured by intravascular ultrasound. The reconstructed images included iodine density maps, conventional images, and different energy levels. The visualization of the stent lumen and stent structure was subjectively assessed using a 4-point Likert scale. The objective evaluation was performed using the in-stent lumen signal-to-noise ratio (SNRis), non-stent lumen SNR (SNRns), internal diameter difference (IDD), and blooming artifact index (BAI). The Friedman test and analysis of variance were used for multiple comparisons.</p><p><strong>Results: </strong>For lumen visualization, the optimal monoenergetic images received the highest score for both group A (2.56±0.51) and group B (3.1±0.55). Multiple comparisons showed that there were significant differences between the optimal monoenergetic images and iodine density maps. However, for stent structure, iodine density maps received the highest score for group A (3.0±0.52) and group B (3.8±0.41). For quantitative assessment, the optimal monoenergetic images had the highest SNRis and SNRns, while the iodine density maps had the lowest SNRis and SNRns. For IDD and BAI, the iodine density maps yielded the smallest value.</p><p><strong>Conclusions: </strong>The monoenergetic images on the second-generation dual-layer detector CT provide better visualization of the lumen and higher SNR. 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引用次数: 0
摘要
背景:重金属伪影阻碍了冠状动脉计算机断层扫描(CT)血管成像评估支架再狭窄的有效性。本研究旨在评估使用 8 厘米双层探测器光谱 CT 进行冠状动脉支架成像的单能重建和碘密度图的图像质量:方法:在这项研究中,使用了 8 个直径为 8 厘米的支架:在管腔显像方面,A 组(2.56±0.51)和 B 组(3.1±0.55)的最佳单能图像得分最高。多重比较显示,最佳单能图像和碘密度图之间存在显著差异。然而,在支架结构方面,碘密度图得分最高的是 A 组(3.0±0.52)和 B 组(3.8±0.41)。在定量评估方面,最佳单能图像的信噪比(SNRis)和信噪比(SNRns)最高,而碘密度图的信噪比(SNRis)和信噪比(SNRns)最低。就 IDD 和 BAI 而言,碘密度图产生的数值最小:结论:第二代双层探测器 CT 上的单能量图像能更好地显示管腔,信噪比也更高。然而,与单能量和传统重建相比,碘密度图在评估支架结构、IDD 和 BAI 方面更胜一筹。
Monoenergetic reconstructions and iodine density maps for visualization of coronary artery stents using 8-cm dual-layer detector spectral computed tomography: an in vitro phantom study.
Background: The effectiveness of coronary computed tomography (CT) angiography in assessing stent restenosis is hindered by heavy metal artifacts. This study aimed to evaluate the image quality of monoenergetic reconstructions and iodine density map for coronary stent imaging using an 8-cm dual-layer detector spectral CT.
Methods: In this study, 8 stents with a diameter <3 mm (group A) and 10 with a diameter ≥3 mm (group B) were placed in plastic tubes filled with iodinated contrast media and scanned. The internal diameter of the prepared stents was then measured by intravascular ultrasound. The reconstructed images included iodine density maps, conventional images, and different energy levels. The visualization of the stent lumen and stent structure was subjectively assessed using a 4-point Likert scale. The objective evaluation was performed using the in-stent lumen signal-to-noise ratio (SNRis), non-stent lumen SNR (SNRns), internal diameter difference (IDD), and blooming artifact index (BAI). The Friedman test and analysis of variance were used for multiple comparisons.
Results: For lumen visualization, the optimal monoenergetic images received the highest score for both group A (2.56±0.51) and group B (3.1±0.55). Multiple comparisons showed that there were significant differences between the optimal monoenergetic images and iodine density maps. However, for stent structure, iodine density maps received the highest score for group A (3.0±0.52) and group B (3.8±0.41). For quantitative assessment, the optimal monoenergetic images had the highest SNRis and SNRns, while the iodine density maps had the lowest SNRis and SNRns. For IDD and BAI, the iodine density maps yielded the smallest value.
Conclusions: The monoenergetic images on the second-generation dual-layer detector CT provide better visualization of the lumen and higher SNR. However, iodine density maps are superior for evaluating stent structure and IDD and BAI compared to monoenergetic and conventional reconstructions.