{"title":"本质性震颤的直接医疗成本。","authors":"Kandice A Kapinos, Elan D Louis","doi":"10.1159/000541968","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>The aim of the study was to determine the direct medical cost of illness from essential tremor (ET) from a patient perspective.</p><p><strong>Methods: </strong>Secondary data from the Optum's de-identified Clinformatics® Data Mart Database from 2018-2019 were used to assess medical resource utilization and costs. Propensity score matching was used to match patients aged 40+ to statistically similar controls. Generalized linear models were used to estimate average, adjusted total costs of care per year, by healthcare setting, and provider specialty.</p><p><strong>Results: </strong>The final sample included 41,200 patients with at least one ET claim and 36,871 matched patients. Overall, ET patients aged 40+ had about USD 28,217 in direct medical costs per year, which was about USD 1,601 more than matched comparisons (p < 0.001). This was driven by greater number of outpatient visits overall and with specialists. Extrapolating the estimates from our study and pairing them with published age-specific disease prevalence statistics for ET, we calculated an annual cost for direct medical care of ET patients aged 40+ to be about USD 9.4 billion.</p><p><strong>Conclusion: </strong>The estimated direct medical costs among adults aged 40+ with an ET diagnosis aggregated to the population level are nontrivial.</p>","PeriodicalId":54730,"journal":{"name":"Neuroepidemiology","volume":" ","pages":"1-7"},"PeriodicalIF":3.2000,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Direct Medical Cost of Essential Tremor.\",\"authors\":\"Kandice A Kapinos, Elan D Louis\",\"doi\":\"10.1159/000541968\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>The aim of the study was to determine the direct medical cost of illness from essential tremor (ET) from a patient perspective.</p><p><strong>Methods: </strong>Secondary data from the Optum's de-identified Clinformatics® Data Mart Database from 2018-2019 were used to assess medical resource utilization and costs. Propensity score matching was used to match patients aged 40+ to statistically similar controls. Generalized linear models were used to estimate average, adjusted total costs of care per year, by healthcare setting, and provider specialty.</p><p><strong>Results: </strong>The final sample included 41,200 patients with at least one ET claim and 36,871 matched patients. Overall, ET patients aged 40+ had about USD 28,217 in direct medical costs per year, which was about USD 1,601 more than matched comparisons (p < 0.001). This was driven by greater number of outpatient visits overall and with specialists. Extrapolating the estimates from our study and pairing them with published age-specific disease prevalence statistics for ET, we calculated an annual cost for direct medical care of ET patients aged 40+ to be about USD 9.4 billion.</p><p><strong>Conclusion: </strong>The estimated direct medical costs among adults aged 40+ with an ET diagnosis aggregated to the population level are nontrivial.</p>\",\"PeriodicalId\":54730,\"journal\":{\"name\":\"Neuroepidemiology\",\"volume\":\" \",\"pages\":\"1-7\"},\"PeriodicalIF\":3.2000,\"publicationDate\":\"2024-10-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Neuroepidemiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1159/000541968\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neuroepidemiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1159/000541968","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
摘要
目的：从患者角度确定本质性震颤（ET）疾病的直接医疗成本：从患者角度确定本质性震颤（ET）疾病的直接医疗成本：采用 Optum 的去标识化 Clinformatics® Data Mart 数据库 (CDM) 中 2018-2019 年的二级数据来评估医疗资源利用率和成本。采用倾向得分匹配法将 40 岁以上的患者与统计上相似的对照组进行匹配。广义线性模型用于估算按医疗机构和医疗服务提供者专业划分的每年平均调整后医疗总成本：最终样本包括 41,200 名至少有一项 ET 申请的患者和 36,871 名匹配患者。总体而言，40 岁以上的 ET 患者每年的直接医疗费用约为 28,217 美元，比匹配的比较者高出约 1,601 美元（p < 0.001）。这主要是由于总体门诊费用和专家门诊费用较高所致。根据我们研究的估算结果，并与已公布的特定年龄段 ET 疾病流行率统计数据进行比对，我们计算出 40 岁以上 ET 患者每年的直接医疗费用约为 94 亿美元：结论：40 岁以上确诊为 ET 的成年人的直接医疗费用在人群中的估计值并不低。
Objectives: The aim of the study was to determine the direct medical cost of illness from essential tremor (ET) from a patient perspective.
Methods: Secondary data from the Optum's de-identified Clinformatics® Data Mart Database from 2018-2019 were used to assess medical resource utilization and costs. Propensity score matching was used to match patients aged 40+ to statistically similar controls. Generalized linear models were used to estimate average, adjusted total costs of care per year, by healthcare setting, and provider specialty.
Results: The final sample included 41,200 patients with at least one ET claim and 36,871 matched patients. Overall, ET patients aged 40+ had about USD 28,217 in direct medical costs per year, which was about USD 1,601 more than matched comparisons (p < 0.001). This was driven by greater number of outpatient visits overall and with specialists. Extrapolating the estimates from our study and pairing them with published age-specific disease prevalence statistics for ET, we calculated an annual cost for direct medical care of ET patients aged 40+ to be about USD 9.4 billion.
Conclusion: The estimated direct medical costs among adults aged 40+ with an ET diagnosis aggregated to the population level are nontrivial.
期刊介绍：
''Neuroepidemiology'' is the only internationally recognised peer-reviewed periodical devoted to descriptive, analytical and experimental studies in the epidemiology of neurologic disease. The scope of the journal expands the boundaries of traditional clinical neurology by providing new insights regarding the etiology, determinants, distribution, management and prevention of diseases of the nervous system.
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