西白梗肾上腺皮质癌:临床和诊断方法。

Brazilian journal of veterinary medicine Pub Date : 2024-10-11 eCollection Date: 2024-01-01 DOI:10.29374/2527-2179.bjvm005424
Fernanda de Paula Sesti, Gabriel Marchiori Gonzaga, Flávia Maria Tavares Manoel Zimmer, Tatiane Viana de Souza Cruz, Bruno Alberigi
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摘要

肾上腺皮质癌 (ACC) 是狗狗的一种罕见疾病。这种类型的肿瘤可以是功能性的,也可以是分泌激素或无功能性的。双侧肾上腺肿瘤并不常见,而单侧肾上腺肿瘤则更为多见。腹部超声波检查是检测这些病变的关键,因为这些病变具有异质性的实质特征。此外,弹性成像(一种评估组织硬度的技术)有助于区分恶性和良性病变。本文描述了一例西高地白梗 ACC 病例。该犬最初表现为皮肤病变和肾上腺组织硬度增加,弹性成像技术检测到了这一点。在进行了包括计算机断层扫描在内的其他检查后,成功实施了肾上腺切除术。组织病理分析证实了 ACC 的诊断。手术后的随访包括定期进行超声波检查,以监测剩余的肾上腺。随访期间发现左侧肾上腺有结节性病变,这凸显了持续监测的重要性。本病例强调了从初步评估到治疗后随访的综合方法对于有效治疗犬 ACC 的重要性。
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Adrenocortical carcinoma in a West White Terrier: clinical and diagnostic approach.

Adrenocortical carcinoma (ACC) is a rare condition in dogs. This type of tumor can be functional, hormone-producing, or nonfunctional. Bilateral adrenal tumors are uncommon, whereas unilateral adrenal tumors are more prevalent. Abdominal ultrasonography is crucial for detecting these lesions, which are characterized by heterogeneous parenchymal characteristics. Furthermore, elastography, a technique that assesses tissue stiffness, is useful for differentiating between malignant and benign lesions. This paper describes a case of ACC in a West Highland white terrier. The dog initially presented with dermatological changes and increased adrenal tissue stiffness, as detected by elastography. After additional examinations, including computed tomography, an adrenalectomy was successfully performed. Histopathological analysis confirmed the diagnosis of ACC. Post-surgical follow-ups included periodic ultrasonography to monitor the remaining adrenal gland. A nodular lesion was identified in the left adrenal gland during the follow-up, highlighting the importance of continuous monitoring. This case underscores the significance of an integrated approach, from the initial evaluation to the post-treatment follow-up for the effective management of ACC in dogs.

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