TearCare 对干眼症患者阅读速度的影响

Clinical ophthalmology (Auckland, N.Z.) Pub Date : 2024-10-10 eCollection Date: 2024-01-01 DOI:10.2147/OPTH.S469300
Yilin Feng, Nandini Venkateswaran, Amanda Steele, Eric D Rosenberg, Preeya K Gupta
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引用次数: 0

摘要

目的:评估 TearCare(TC)治疗对干眼症(DED)和睑板腺疾病(MGD)患者的临床、生活质量和功能性视觉结果指标的影响:这是一项前瞻性的单中心临床试验。方法:这是一项前瞻性的单中心临床试验:共纳入 32 名受试者。平均年龄为 55.9 岁。16 名受试者(52%)在接受 TC 治疗后,阅读速度有了临床意义上的显著提高,即 IReST 分数每分钟提高 10 个单词以上。IReST 和 MNREAD 的改善达到了统计学意义(分别为 p = 0.012 和 p = 0.028)。TC 治疗后,OSDI 评分明显下降,VFQ-25 评分明显上升(p < 0.001)。治疗后,所有临床检查指标均有统计学意义的改善(p < 0.001):TC在临床和视觉功能方面都是一种有效的治疗方法。接受 TC 治疗的患者在接受一次治疗后,生活质量得到改善,阅读速度也有所提高。应经常考虑并使用这种治疗方法,以减轻与多发性硬化症相关的 DED 疾病负担。
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Impact of TearCare on Reading Speed in Patients with Dry Eye Disease.

Purpose: To evaluate the impact of TearCare (TC) treatment on clinical, quality of life, and functional visual outcome metrics in patients with dry eye disease (DED) and meibomian gland disease (MGD).

Methods: This is a prospective, single-center clinical trial. Adults with MGD and a DED diagnosis and tear break-up time (TBUT) <10 seconds were included. All subjects had at least 20/40 vision and no surgery or new treatment for DED within 60 days prior to enrollment. All patients had one baseline visit prior to undergoing TC and one follow-up visit 1 month after TC. At each visit, the meibomian gland secretion score (MGSS), TBUT, and corneal fluorescein staining (KFL) were assessed. DED symptoms were evaluated using the Ocular Surface Disease Index (OSDI) questionnaire, Visual Function Questionnaire 25 (VFQ-25), and the Fatigue Severity Scale. Reading speed was determined through the International Reading Speed Texts (IReST), Minnesota Low Vision Reading Test (MNREAD), and Wilkins Rate of Reading Test (WRRT).

Results: Thirty-two subjects were included. The average age was 55.9 years. Sixteen (52%) participants had a clinically significant improvement in reading speed after treatment with TC, defined as >10 words per minute increase in their IReST score. Improvement on the IReST and the MNREAD reached statistical significance (p = 0.012 and p = 0.028, respectively). OSDI scores significantly decreased and VFQ-25 scores significantly increased after TC treatment (p < 0.001). All of the clinical exam parameters showed statistically significant improvements after treatment (p < 0.001).

Conclusion: TC is an effective treatment both clinically and with respect to visual function. Patients who had TC exhibited improvements in quality of life and improved reading speed after a single treatment. This treatment should be frequently considered and utilized to reduce the disease burden of DED related to MGD.

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