{"title":"利用基于熵的矩阵从单信道脑电信号检测多种精神障碍的轻量级方法。","authors":"Jiawen Li, Guanyuan Feng, Jujian Lv, Yanmei Chen, Rongjun Chen, Fei Chen, Shuang Zhang, Mang-I Vai, Sio-Hang Pun, Peng-Un Mak","doi":"10.3390/brainsci14100987","DOIUrl":null,"url":null,"abstract":"<p><p><b>Background</b>: Mental health issues are increasingly prominent worldwide, posing significant threats to patients and deeply affecting their families and social relationships. Traditional diagnostic methods are subjective and delayed, indicating the need for an objective and effective early diagnosis method. <b>Methods</b>: To this end, this paper proposes a lightweight detection method for multi-mental disorders with fewer data sources, aiming to improve diagnostic procedures and enable early patient detection. First, the proposed method takes Electroencephalography (EEG) signals as sources, acquires brain rhythms through Discrete Wavelet Decomposition (DWT), and extracts their approximate entropy, fuzzy entropy, permutation entropy, and sample entropy to establish the entropy-based matrix. Then, six kinds of conventional machine learning classifiers, including Support Vector Machine (SVM), k-Nearest Neighbors (kNN), Naive Bayes (NB), Generalized Additive Model (GAM), Linear Discriminant Analysis (LDA), and Decision Tree (DT), are adopted for the entropy-based matrix to achieve the detection task. Their performances are assessed by accuracy, sensitivity, specificity, and F1-score. Concerning these experiments, three public datasets of schizophrenia, epilepsy, and depression are utilized for method validation. <b>Results</b>: The analysis of the results from these datasets identifies the representative single-channel signals (schizophrenia: O1, epilepsy: F3, depression: O2), satisfying classification accuracies (88.10%, 75.47%, and 89.92%, respectively) with minimal input. <b>Conclusions</b>: Such performances are impressive when considering fewer data sources as a concern, which also improves the interpretability of the entropy features in EEG, providing a reliable detection approach for multi-mental disorders and advancing insights into their underlying mechanisms and pathological states.</p>","PeriodicalId":9095,"journal":{"name":"Brain Sciences","volume":"14 10","pages":""},"PeriodicalIF":2.7000,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11505710/pdf/","citationCount":"0","resultStr":"{\"title\":\"A Lightweight Multi-Mental Disorders Detection Method Using Entropy-Based Matrix from Single-Channel EEG Signals.\",\"authors\":\"Jiawen Li, Guanyuan Feng, Jujian Lv, Yanmei Chen, Rongjun Chen, Fei Chen, Shuang Zhang, Mang-I Vai, Sio-Hang Pun, Peng-Un Mak\",\"doi\":\"10.3390/brainsci14100987\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b>Background</b>: Mental health issues are increasingly prominent worldwide, posing significant threats to patients and deeply affecting their families and social relationships. 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引用次数: 0
摘要
背景:精神健康问题在全球范围内日益突出,对患者构成重大威胁,并深深影响着他们的家庭和社会关系。传统的诊断方法具有主观性和延迟性,因此需要一种客观有效的早期诊断方法。方法:为此,本文提出了一种数据源较少的多种精神障碍轻量级检测方法,旨在改进诊断程序,实现早期发现患者。首先,该方法以脑电信号为数据源,通过离散小波分解(DWT)获取脑节奏,并提取其近似熵、模糊熵、置换熵和样本熵,建立基于熵的矩阵。然后,对基于熵的矩阵采用六种传统机器学习分类器,包括支持向量机(SVM)、k-近邻(kNN)、奈夫贝叶斯(NB)、广义相加模型(GAM)、线性判别分析(LDA)和决策树(DT),以实现检测任务。它们的性能通过准确度、灵敏度、特异性和 F1 分数进行评估。在这些实验中,使用了精神分裂症、癫痫和抑郁症三个公共数据集进行方法验证。实验结果对这些数据集的结果进行分析,确定了具有代表性的单通道信号(精神分裂症:O1;癫痫:F3;抑郁症:O2),以最小的输入达到了令人满意的分类准确率(分别为 88.10%、75.47% 和 89.92%)。结论考虑到数据源较少,这种性能令人印象深刻,同时也提高了脑电图中熵特征的可解释性,为多种精神疾病提供了一种可靠的检测方法,并推进了对其潜在机制和病理状态的深入了解。
A Lightweight Multi-Mental Disorders Detection Method Using Entropy-Based Matrix from Single-Channel EEG Signals.
Background: Mental health issues are increasingly prominent worldwide, posing significant threats to patients and deeply affecting their families and social relationships. Traditional diagnostic methods are subjective and delayed, indicating the need for an objective and effective early diagnosis method. Methods: To this end, this paper proposes a lightweight detection method for multi-mental disorders with fewer data sources, aiming to improve diagnostic procedures and enable early patient detection. First, the proposed method takes Electroencephalography (EEG) signals as sources, acquires brain rhythms through Discrete Wavelet Decomposition (DWT), and extracts their approximate entropy, fuzzy entropy, permutation entropy, and sample entropy to establish the entropy-based matrix. Then, six kinds of conventional machine learning classifiers, including Support Vector Machine (SVM), k-Nearest Neighbors (kNN), Naive Bayes (NB), Generalized Additive Model (GAM), Linear Discriminant Analysis (LDA), and Decision Tree (DT), are adopted for the entropy-based matrix to achieve the detection task. Their performances are assessed by accuracy, sensitivity, specificity, and F1-score. Concerning these experiments, three public datasets of schizophrenia, epilepsy, and depression are utilized for method validation. Results: The analysis of the results from these datasets identifies the representative single-channel signals (schizophrenia: O1, epilepsy: F3, depression: O2), satisfying classification accuracies (88.10%, 75.47%, and 89.92%, respectively) with minimal input. Conclusions: Such performances are impressive when considering fewer data sources as a concern, which also improves the interpretability of the entropy features in EEG, providing a reliable detection approach for multi-mental disorders and advancing insights into their underlying mechanisms and pathological states.
期刊介绍:
Brain Sciences (ISSN 2076-3425) is a peer-reviewed scientific journal that publishes original articles, critical reviews, research notes and short communications in the areas of cognitive neuroscience, developmental neuroscience, molecular and cellular neuroscience, neural engineering, neuroimaging, neurolinguistics, neuropathy, systems neuroscience, and theoretical and computational neuroscience. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. Electronic files or software regarding the full details of the calculation and experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material.