等待手术治疗的基底细胞癌(BCC)的自然发展。

IF 2.8 4区 医学 Q1 DERMATOLOGY Clinical and Experimental Dermatology Pub Date : 2025-02-24 DOI:10.1093/ced/llae460
Mun W Lam, Helena Wells, Andrew Zhao, Heidi Gibbs, Simon Tso, Aaron Wernham
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引用次数: 0

摘要

基底细胞癌(BCC)是一种生长缓慢的角质细胞肿瘤,有关未经治疗的 BCC 自然病史的文献报道十分有限。本研究评估了BCC在等待手术治疗期间的自然进展和患者预后。数据收集只包括经组织学证实的 BCC 患者。研究对55名患者(共70个病灶)进行了回顾性数据分析,结果显示,BCC的平均生长速度与等待手术的时间之间存在统计学意义上的显著相关性。20%的病例的手术规模大于预约时的原计划。报告的前三位症状包括瘙痒(39.4%)、结痂(36.4%)和出血(30.3%)。总之,我们发现 BCC 的生长与患者从初次就诊到接受手术治疗的时间长度之间存在正相关关系,患者最终往往会出现更多症状,接受比原计划更大、更复杂的手术,尤其是在头颈部。
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Natural progression of basal cell carcinomas in patients awaiting surgical intervention.

Basal cell carcinomas (BCCs) are slow-growing keratinocyte tumours. There are few reports in the literature reporting the natural history of untreated BCCs. We evaluated the natural progression of BCCs and patient outcomes while awaiting surgical intervention. Only patients with histologically proven BCCs were included in our analysis. Retrospective data analysis was performed for a sample of 55 patients (in total, 70 lesions). There was a significant correlation between the average growth of BCCs and the time waiting for a procedure, with 20% of patients requiring a more complex procedure than originally planned at the time of booking. The top three most frequently reported symptoms were itching (39.4%), crusting (36.4%) and bleeding (30.3%). We report a positive relationship between BCC growth and the length of time from initial presentation to surgical treatment. Patients with long waits often exhibited more symptoms and required more complex surgical procedures than originally planned, especially for BCCs in the head and neck.

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来源期刊
CiteScore
3.20
自引率
2.40%
发文量
389
审稿时长
3-8 weeks
期刊介绍: Clinical and Experimental Dermatology (CED) is a unique provider of relevant and educational material for practising clinicians and dermatological researchers. We support continuing professional development (CPD) of dermatology specialists to advance the understanding, management and treatment of skin disease in order to improve patient outcomes.
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