等待手术治疗的基底细胞癌(BCC)的自然发展。

IF 3.7 4区 医学 Q1 DERMATOLOGY Clinical and Experimental Dermatology Pub Date : 2024-10-24 DOI:10.1093/ced/llae460
Mun Wai Lam, Helena Wells, Andrew Zhao, Heidi Gibbs, Simon Tso, Aaron Wernham
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引用次数: 0

摘要

基底细胞癌(BCC)是一种生长缓慢的角质细胞肿瘤,有关未经治疗的 BCC 自然病史的文献报道十分有限。本研究评估了BCC在等待手术治疗期间的自然进展和患者预后。数据收集只包括经组织学证实的 BCC 患者。研究对55名患者(共70个病灶)进行了回顾性数据分析,结果显示,BCC的平均生长速度与等待手术的时间之间存在统计学意义上的显著相关性。20%的病例的手术规模大于预约时的原计划。报告的前三位症状包括瘙痒(39.4%)、结痂(36.4%)和出血(30.3%)。总之,我们发现 BCC 的生长与患者从初次就诊到接受手术治疗的时间长度之间存在正相关关系,患者最终往往会出现更多症状,接受比原计划更大、更复杂的手术,尤其是在头颈部。
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The natural progression of basal cell carcinomas (BCCs) awaiting surgical intervention.

Basal cell carcinomas (BCCs) are slow growing keratinocyte tumours with limited literature reporting the natural history of untreated BCCs. This study evaluated the natural progression and patient outcomes of BCCs whilst awaiting surgical intervention. Only patients with histologically proven BCCs were included in the data collection. Retrospective data analysis was performed on 55 patients (total of 70 lesions) and showed a statistically significant correlation between average growth of BCCs and time waiting for a procedure. Twenty percent of the cases had a larger procedure than originally planned at the time of booking. The top three symptoms reported include itching (39.4%), crusting (36.4%) and bleeding (30.3%). In conclusion, we reported a positive relationship between BCC growth and length of time from initial presentation to surgical treatment where patients often ended up with more symptoms, larger and complex surgical procedure than originally planned especially on the head and neck.

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来源期刊
CiteScore
3.20
自引率
2.40%
发文量
389
审稿时长
3-8 weeks
期刊介绍: Clinical and Experimental Dermatology (CED) is a unique provider of relevant and educational material for practising clinicians and dermatological researchers. We support continuing professional development (CPD) of dermatology specialists to advance the understanding, management and treatment of skin disease in order to improve patient outcomes.
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