Caryopteris trichosphaera 中的两种新的abietane diterpenoids。

IF 2.5 3区 医学 Q3 CHEMISTRY, MEDICINAL Fitoterapia Pub Date : 2024-10-23 DOI:10.1016/j.fitote.2024.106269
Qing-Yu Lu , Zhao-Jie Wang , Li-Yu Bai , Wen-Biao Zu , Zhong-Shun Zhou , Yan-Yan Zhu , Xing-Chao He , Yun-Li Zhao , Xiao-Dong Luo
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引用次数: 0

摘要

从 Caryopteris trichosphaera 中分离出了两种新的abietane二萜类化合物,即 cartrisine A (1) 和 cartrisine B (2)。根据 HR-ESI-MS 和 NMR 光谱数据阐明了它们的结构。化合物 2 对 MRSA 和 VRE 具有中等程度的抗菌生物活性,并与市场上的抗生素对 MRSA 和 VRE 具有较强的协同作用。
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Two new abietane diterpenoids from Caryopteris trichosphaera
Two new abietane diterpenoids, cartrisine A (1) and cartrisine B (2) were isolated from Caryopteris trichosphaera. Their structures were elucidated based on HR-ESI-MS and NMR spectral data. Compound 2 exhibited moderate antibacterial bioactivity against MRSA and VRE, and showed a strong synergistic effect with market antibiotics against MRSA and VRE.
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来源期刊
Fitoterapia
Fitoterapia 医学-药学
CiteScore
5.80
自引率
2.90%
发文量
198
审稿时长
1.5 months
期刊介绍: Fitoterapia is a Journal dedicated to medicinal plants and to bioactive natural products of plant origin. It publishes original contributions in seven major areas: 1. Characterization of active ingredients of medicinal plants 2. Development of standardization method for bioactive plant extracts and natural products 3. Identification of bioactivity in plant extracts 4. Identification of targets and mechanism of activity of plant extracts 5. Production and genomic characterization of medicinal plants biomass 6. Chemistry and biochemistry of bioactive natural products of plant origin 7. Critical reviews of the historical, clinical and legal status of medicinal plants, and accounts on topical issues.
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