Xiang Zhou, Xishan Li, Kai Oliver Böker, Arndt F Schilling, Wolfgang Lehmann
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The purpose of this study was to investigate the biomechanical behavior of positive reduction across different Pauwels classification, providing a reference for quantifying positive reduction in clinical practice.</p><p><strong>Methods: </strong>Three-dimensional (3D) models of FNF were established and categorized according to the Pauwels classifications (Pauwels I, II, and III), each of them contained seven models with different reduction qualities, including an anatomical reduction model, two negative reduction models, and four positive reduction models, all of which were stabilized with dynamic hip screws (DHS) and cannulated screws (CS). We investigated the maximal von-Mises stress of internal fixation and proximal femoral, femoral fragment displacement, and maximal von-Mises strain at the proximal fragment fracture site when a 2100 N load was applied to the femoral head.</p><p><strong>Results: </strong>The maximum von-Mises stress on the internal fixators in each Pauwels group was lowest in the anatomical reduction model. In the Pauwels I group, positive reduction exceeding 3 mm resulted in the maximum von-Mises stress on the internal fixators surpassing that of the negative reduction model. For the Pauwels II group, positive reduction beyond 2 mm led to the maximum von-Mises stress on the internal fixators exceeding that of the negative reduction model. In the Pauwels III group, positive reduction beyond 1 mm caused the maximum von-Mises stress on the internal fixators to be higher than that of the negative reduction model. The maximum von-Mises strain at the fracture site of proximal femur fragment increased with positive reduction. Varus displacement increased in positive reduction models as the Pauwels angle rose, potentially exacerbating rotation deformity in Pauwels III group.</p><p><strong>Conclusion: </strong>Excessive positive reduction may increase the risk of FNF failure after internal fixation. From a biomechanical stability perspective, positive reduction should be limited to 3 mm or below in the Pauwels I group, restricted to not exceed 2 mm in the Pauwels II group, and should not exceed 1 mm in the Pauwels III group. Negative reduction should be avoided in all Pauwels groups.</p>","PeriodicalId":12444,"journal":{"name":"Frontiers in Bioengineering and Biotechnology","volume":null,"pages":null},"PeriodicalIF":4.3000,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11496117/pdf/","citationCount":"0","resultStr":"{\"title\":\"Biomechanical investigation of positive reduction in the femoral neck fracture: a finite element analysis.\",\"authors\":\"Xiang Zhou, Xishan Li, Kai Oliver Böker, Arndt F Schilling, Wolfgang Lehmann\",\"doi\":\"10.3389/fbioe.2024.1374299\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Gotfried positive reduction offers an alternative strategy for femoral neck fracture (FNF) when achieving anatomical reduction is challenging. However, the biomechanical consequences of positive reduction remain unclear. The purpose of this study was to investigate the biomechanical behavior of positive reduction across different Pauwels classification, providing a reference for quantifying positive reduction in clinical practice.</p><p><strong>Methods: </strong>Three-dimensional (3D) models of FNF were established and categorized according to the Pauwels classifications (Pauwels I, II, and III), each of them contained seven models with different reduction qualities, including an anatomical reduction model, two negative reduction models, and four positive reduction models, all of which were stabilized with dynamic hip screws (DHS) and cannulated screws (CS). We investigated the maximal von-Mises stress of internal fixation and proximal femoral, femoral fragment displacement, and maximal von-Mises strain at the proximal fragment fracture site when a 2100 N load was applied to the femoral head.</p><p><strong>Results: </strong>The maximum von-Mises stress on the internal fixators in each Pauwels group was lowest in the anatomical reduction model. In the Pauwels I group, positive reduction exceeding 3 mm resulted in the maximum von-Mises stress on the internal fixators surpassing that of the negative reduction model. For the Pauwels II group, positive reduction beyond 2 mm led to the maximum von-Mises stress on the internal fixators exceeding that of the negative reduction model. In the Pauwels III group, positive reduction beyond 1 mm caused the maximum von-Mises stress on the internal fixators to be higher than that of the negative reduction model. The maximum von-Mises strain at the fracture site of proximal femur fragment increased with positive reduction. Varus displacement increased in positive reduction models as the Pauwels angle rose, potentially exacerbating rotation deformity in Pauwels III group.</p><p><strong>Conclusion: </strong>Excessive positive reduction may increase the risk of FNF failure after internal fixation. From a biomechanical stability perspective, positive reduction should be limited to 3 mm or below in the Pauwels I group, restricted to not exceed 2 mm in the Pauwels II group, and should not exceed 1 mm in the Pauwels III group. 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引用次数: 0
摘要
背景:当实现解剖复位具有挑战性时,戈特弗里德正位复位术为股骨颈骨折(FNF)提供了一种替代策略。然而,积极复位的生物力学后果仍不清楚。本研究的目的是调查不同 Pauwels 分类下积极复位的生物力学行为,为临床实践中量化积极复位提供参考:建立了 FNF 的三维(3D)模型,并根据 Pauwels 分级(Pauwels I、II 和 III)进行了分类,每个分类包含 7 个不同减径质量的模型,其中包括一个解剖减径模型、两个负减径模型和四个正减径模型,所有模型均使用动态髋关节螺钉(DHS)和套管螺钉(CS)进行稳定。我们研究了股骨头承受2100牛载荷时,内固定和股骨近端最大von-Mises应力、股骨碎片位移以及近端碎片骨折部位的最大von-Mises应变:在解剖复位模型中,每个 Pauwels 组内固定器上的最大 von-Mises 应力最小。在 Pauwels I 组中,正减径超过 3 mm 时,内固定器上的最大 von-Mises 应力超过了负减径模型。在 Pauwels II 组中,正向缩减超过 2 mm 会导致内固定器上的最大 von-Mises 应力超过负向缩减模型。在 Pauwels III 组中,正向缩减超过 1 mm 会导致内固定器上的最大 von-Mises 应力高于负向缩减模型。股骨近端骨折部位的最大 von-Mises 应变随着正位复位而增加。随着Pauwels角的增大,正位复位模型中的屈曲移位也随之增大,这可能会加剧Pauwels III组的旋转畸形:结论:过度正位复位可能会增加内固定后 FNF 失败的风险。从生物力学稳定性的角度来看,Pauwels I 组的正缩应限制在 3 毫米或以下,Pauwels II 组不应超过 2 毫米,Pauwels III 组不应超过 1 毫米。所有 Pauwels 组均应避免负缩减。
Biomechanical investigation of positive reduction in the femoral neck fracture: a finite element analysis.
Background: Gotfried positive reduction offers an alternative strategy for femoral neck fracture (FNF) when achieving anatomical reduction is challenging. However, the biomechanical consequences of positive reduction remain unclear. The purpose of this study was to investigate the biomechanical behavior of positive reduction across different Pauwels classification, providing a reference for quantifying positive reduction in clinical practice.
Methods: Three-dimensional (3D) models of FNF were established and categorized according to the Pauwels classifications (Pauwels I, II, and III), each of them contained seven models with different reduction qualities, including an anatomical reduction model, two negative reduction models, and four positive reduction models, all of which were stabilized with dynamic hip screws (DHS) and cannulated screws (CS). We investigated the maximal von-Mises stress of internal fixation and proximal femoral, femoral fragment displacement, and maximal von-Mises strain at the proximal fragment fracture site when a 2100 N load was applied to the femoral head.
Results: The maximum von-Mises stress on the internal fixators in each Pauwels group was lowest in the anatomical reduction model. In the Pauwels I group, positive reduction exceeding 3 mm resulted in the maximum von-Mises stress on the internal fixators surpassing that of the negative reduction model. For the Pauwels II group, positive reduction beyond 2 mm led to the maximum von-Mises stress on the internal fixators exceeding that of the negative reduction model. In the Pauwels III group, positive reduction beyond 1 mm caused the maximum von-Mises stress on the internal fixators to be higher than that of the negative reduction model. The maximum von-Mises strain at the fracture site of proximal femur fragment increased with positive reduction. Varus displacement increased in positive reduction models as the Pauwels angle rose, potentially exacerbating rotation deformity in Pauwels III group.
Conclusion: Excessive positive reduction may increase the risk of FNF failure after internal fixation. From a biomechanical stability perspective, positive reduction should be limited to 3 mm or below in the Pauwels I group, restricted to not exceed 2 mm in the Pauwels II group, and should not exceed 1 mm in the Pauwels III group. Negative reduction should be avoided in all Pauwels groups.
期刊介绍:
The translation of new discoveries in medicine to clinical routine has never been easy. During the second half of the last century, thanks to the progress in chemistry, biochemistry and pharmacology, we have seen the development and the application of a large number of drugs and devices aimed at the treatment of symptoms, blocking unwanted pathways and, in the case of infectious diseases, fighting the micro-organisms responsible. However, we are facing, today, a dramatic change in the therapeutic approach to pathologies and diseases. Indeed, the challenge of the present and the next decade is to fully restore the physiological status of the diseased organism and to completely regenerate tissue and organs when they are so seriously affected that treatments cannot be limited to the repression of symptoms or to the repair of damage. This is being made possible thanks to the major developments made in basic cell and molecular biology, including stem cell science, growth factor delivery, gene isolation and transfection, the advances in bioengineering and nanotechnology, including development of new biomaterials, biofabrication technologies and use of bioreactors, and the big improvements in diagnostic tools and imaging of cells, tissues and organs.
In today`s world, an enhancement of communication between multidisciplinary experts, together with the promotion of joint projects and close collaborations among scientists, engineers, industry people, regulatory agencies and physicians are absolute requirements for the success of any attempt to develop and clinically apply a new biological therapy or an innovative device involving the collective use of biomaterials, cells and/or bioactive molecules. “Frontiers in Bioengineering and Biotechnology” aspires to be a forum for all people involved in the process by bridging the gap too often existing between a discovery in the basic sciences and its clinical application.