病例报告:孕产妇大出血及其与新生儿明显贫血的关联。

IF 2.1 3区 医学 Q2 PEDIATRICS Frontiers in Pediatrics Pub Date : 2024-10-08 eCollection Date: 2024-01-01 DOI:10.3389/fped.2024.1423786
Peng Li, Hua Shu, Peng Lin, Jishui Wang, Di Zhang, Dongmei Man, Fengge Wang
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引用次数: 0

摘要

孕产妇出血(Fetomaternal hemorrhage,FMH)是一种令人困惑的产科疾病,主要发生在妊娠三个月或分娩时。它起病隐匿且无特异性,常常给诊断带来困难。尽管主要归因于胎盘屏障受损,但对 FMH 的基本病理生理学仍不完全清楚。病情的严重程度与失血量、出血率和异体免疫有内在联系。一旦发生严重的 FMH,就会迅速导致宫内窘迫、胎儿贫血和胎儿死亡的可能性,从而对产妇和新生儿的健康构成巨大威胁。在这篇文章中,我介绍了一例大量的 FMH 病例,并对目前有关该病症的病因、临床表现、诊断方法、治疗要点和预后的科学文献进行了系统回顾。这项工作旨在提高临床医生对 FMH 的理解和诊断能力。
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Case Report: Fetomaternal hemorrhage and its association with pronounced neonatal anemia.

Fetomaternal hemorrhage (FMH) is a perplexing obstetric condition that predominantly occurs during the third trimester or at the time of delivery. Its insidious and non-specific onset often leads to diagnostic challenges. The underlying pathophysiology of FMH remains incompletely understood, though it is primarily attributed to compromise of the placental barrier. The severity of the condition is intrinsically associated with the volumn of blood loss, the hemorrhage rate, and the presence of alloimmunity. Upon the occurrence of severe FMH, it can rapidly lead to intrauterine distress, fetal anemia, and the possibility of fetal demise, presenting a considerable threat to both maternal and neonatal well-being. In this article, I present a substantial case of FMH and conduct a systematic review of the current scientific literature regarding the etiology, clinical manifestations, diagnostic approaches, treatment highlights, and prognosis of this condition. The objective of this work is to improve clinicians' comprehension and diagnostic proficiency concerning FMH.

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来源期刊
Frontiers in Pediatrics
Frontiers in Pediatrics Medicine-Pediatrics, Perinatology and Child Health
CiteScore
3.60
自引率
7.70%
发文量
2132
审稿时长
14 weeks
期刊介绍: Frontiers in Pediatrics (Impact Factor 2.33) publishes rigorously peer-reviewed research broadly across the field, from basic to clinical research that meets ongoing challenges in pediatric patient care and child health. Field Chief Editors Arjan Te Pas at Leiden University and Michael L. Moritz at the Children''s Hospital of Pittsburgh are supported by an outstanding Editorial Board of international experts. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide. Frontiers in Pediatrics also features Research Topics, Frontiers special theme-focused issues managed by Guest Associate Editors, addressing important areas in pediatrics. In this fashion, Frontiers serves as an outlet to publish the broadest aspects of pediatrics in both basic and clinical research, including high-quality reviews, case reports, editorials and commentaries related to all aspects of pediatrics.
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