用于计算机断层扫描引导同步经皮肺活检和肺结节微波消融的电磁导航系统:一项前瞻性、单中心、单臂临床研究。

IF 3 3区 医学 Q2 ONCOLOGY International Journal of Hyperthermia Pub Date : 2024-01-01 Epub Date: 2024-10-27 DOI:10.1080/02656736.2024.2417761
Shengwei Li, Zhixin Bie, Yuanming Li, Jie Sun, Jiangxu Zhang, Xiangyu Zi, Runqi Guo, Xiao-Guang Li
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引用次数: 0

摘要

研究背景本研究的目的是对计算机断层扫描(CT)引导下同步经皮肺活检和肺结节微波消融(MWA)的电磁导航系统(EMN)的安全性和有效性进行临床评估:这项前瞻性、单中心、单臂临床队列研究于2023年3月至2023年5月在北京医院进行。本研究前瞻性地纳入了在 CT 引导下通过 EMN 系统进行同步经皮肺活检和 MWA 的患者。所有介入手术均由同一位介入放射科医生完成。活检和MWA的技术成功率、技术有效率作为主要结果进行评估。我们还记录并分析了每位患者的术前、术中和术后变量:结果:共有 48 名患者参与了研究。技术成功率为 100%。活检的技术有效率为 95.8%(46/48),WMA 的技术有效率为 100%(48/48),随访期间无复发。胸膜下针道总长度和距离误差分别为(8.3 ± 2.6)厘米、(3.6 ± 1.6)厘米和(1.84 ± 1.08)毫米。针头调整次数和 CT 采集次数的中位数分别为 1 次(1-3 次不等)和 3 次(3-5 次不等)。到达目标时间和手术时间分别为 4.4 ± 1.7 分钟和 19.7 ± 5.2 分钟。剂量长度乘积为 748.8 ± 221.8 mGy*cm。术后中位住院时间为1天(1-7天不等)。无重大并发症(≥3 级)发生,仅有 7 例轻微并发症(14.6%),包括 6 例气胸和 1 例咯血。放射科医生术后的满意度很高:结论:EMN系统用于CT引导下同步经皮肺活检和肺结节MWA是可行、安全和有效的。
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Electromagnetic navigation system for computed tomography-guided synchronous percutaneous lung biopsy and microwave ablation of pulmonary nodules: a prospective, single-center, single-arm clinical study.

Background: The purpose of this study was to clinically evaluate the safety and effectiveness of the electromagnetic navigation (EMN) system designed for computed tomography (CT)-guided synchronous percutaneous lung biopsy and microwave ablation (MWA) of pulmonary nodules.

Methods: This prospective, single-center, single-arm clinical cohort study was conducted in Beijing Hospital from March 2023 to May 2023. Patients who underwent CT-guided synchronous percutaneous lung biopsy and MWA via the EMN system were prospectively enrolled in our study. All the interventional procedures were performed by the same interventional radiologist. The technical success rate, the technical efficacy rates of biopsy and MWA were assessed as the primary outcomes. Preoperative, intraoperative, and postoperative variables were also recorded and analyzed for each patient.

Results: A total of 48 patients were enrolled in the study. The technical success rate was 100%. The technical efficacy rate of biopsy was 95.8% (46/48), and the technical efficacy rate of WMA was 100% (48/48) with no recurrence during follow-up. The total and subpleural needle trajectory length and distance error were 8.3 ± 2.6 cm, 3.6 ± 1.6 cm, and 1.84 ± 1.08 mm, respectively. The median numbers of needle adjustments and CT acquisitions were 1 (range 1-3) and 3 (range 3-5), respectively. The time to reach the target and procedure time were 4.4 ± 1.7 and 19.7 ± 5.2 min, respectively. The dose length product was 748.8 ± 221.8 mGy*cm. The median postoperative hospital stay was 1 (range 1-7) days. No major complications (grade ≥3) occurred and only seven minor complications (14.6%) occurred, including six cases of pneumothorax and one case of hemoptysis. The radiologists achieved high satisfaction scores after surgery.

Conclusion: The EMN system is feasible, safe and effective for CT-guided synchronous percutaneous lung biopsy and MWA of pulmonary nodules.

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来源期刊
CiteScore
5.90
自引率
12.90%
发文量
153
审稿时长
6-12 weeks
期刊介绍: The International Journal of Hyperthermia
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