用于模拟人体直肠排便过程的生物启发圆形软驱动器。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-10-23 DOI:10.1007/s10047-024-01477-5
Zebing Mao, Sota Suzuki, Ardi Wiranata, Yanqiu Zheng, Shoko Miyagawa
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引用次数: 0

摘要

软体机器人在医疗领域有着广泛的应用,尤其是在康复训练、辅助抓取和人造器官方面。尽管在模拟消化系统各组成部分方面取得了重大进展,但由于社会偏见,直肠在很大程度上一直被忽视。本研究试图通过开发软性环形肌肉致动器(CMA)和直肠模型来复制排便过程,从而弥补这一不足。我们使用软质材料制作直肠和致动器,以实现无缝集成和连接。我们设计、制造并测试了三种类型的 CMA,并将它们与模拟结果进行了比较。我们采用气动系统控制致动器,并使用海藻酸钠和氯化钙合成了模拟粪便。实验结果表明,第三种致动器在产生压力方面表现出色,使面积收缩达到最大值 1。排便过程的成功模拟凸显了这些软致动器在生物医学应用中的潜力,为软机器人领域的进一步研究和开发奠定了基础。
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Bio-inspired circular soft actuators for simulating defecation process of human rectum.

Soft robots have found extensive applications in the medical field, particularly in rehabilitation exercises, assisted grasping, and artificial organs. Despite significant advancements in simulating various components of the digestive system, the rectum has been largely neglected due to societal stigma. This study seeks to address this gap by developing soft circular muscle actuators (CMAs) and rectum models to replicate the defecation process. Using soft materials, both the rectum and the actuators were fabricated to enable seamless integration and attachment. We designed, fabricated, and tested three types of CMAs and compared them to the simulated results. A pneumatic system was employed to control the actuators, and simulated stool was synthesized using sodium alginate and calcium chloride. Experimental results indicated that the third type of actuator exhibited superior performance in pressure generation, enabling the area contraction to reach a maximum value of 1. The successful simulation of the defecation process highlights the potential of these soft actuators in biomedical applications, providing a foundation for further research and development in the field of soft robotics.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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