在伦敦一家教学医院急诊科就诊的成人中选择不接受艾滋病毒筛查。

IF 4 3区 医学 Q2 VIROLOGY Journal of Clinical Virology Pub Date : 2024-10-08 DOI:10.1016/j.jcv.2024.105735
Raissa Rachman , Tanzina Haque , Tristan J Barber , Fiona Burns , Jessica Pinto , Alan Hunter , Russell Durkin , Jennifer Hart
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引用次数: 0

摘要

背景:根据英国国家医疗服务体系(NHSEI)和英国国家医疗服务体系改进(NHS Improvement)计划,皇家自由医院引入了急诊科血液传播病毒(EDBBV)选择性筛查,在艾滋病高发地区扩大选择性检测范围。这一举措是 "迈向零 "政策的一部分,旨在到 2030 年在英格兰杜绝 HIV 传播:所有在皇家自由医院急诊科(ED)就诊的 16 岁及以上患者都要接受血液传播病毒(HIV/HBV/HCV)筛查,除非他们选择不接受筛查。我们研究了自 2022 年 4 月 12 日开始进行 EDBBV 检测至 8 月 12 日期间急诊科就诊患者的 HIV 数据。乙肝和丙肝数据在另一项研究中进行了审查:共对来自 10,641 名患者的 12,208 份样本进行了艾滋病毒筛查。在这些样本中,有 88 份呈阳性,血清阳性率为 0.84%。其中有 48 名患者已在当地的 HIV 服务机构接受过检测,35 名患者在信托基金以外的 HIV 服务机构接受过检测,5 名患者是新诊断出的:我们的结果证实,根据英国卫生安全局的数据,我们当地的 HIV 感染率非常高,因此有必要进行 HIV 检测。选择不接受 ED BBV 筛查是一种非常有效的方法,可以识别不知道自己感染情况的 HIV 感染者。
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Opt-out HIV screening in adults attending the Emergency Department of a London teaching hospital

Background

Opt-out Emergency Department blood borne virus (EDBBV) screening was introduced at the Royal Free Hospital under the NHSEI (NHS England and NHS Improvement) programme to expand opt-out testing in local authority areas with high HIV prevalence. This initiative was part of the “Toward Zero” policy towards ending HIV transmission in England by 2030.

Methods

All patients attending the Royal Free Hospital Emergency Department (ED) aged 16 and over were screened for blood borne viruses (HIV/HBV/HCV) unless they opted out. We looked at HIV data from patients seen in ED between the initiation of EDBBV testing on the 12th of April and 12th of August 2022. Hepatitis B and C data was reviewed in a separate study.

Outcome

A total of 12,208 samples from 10,641 patients were screened for HIV. Amongst these samples there were 88 which were positive, giving a seroprevalence of 0.84 %. There were 48 patients who were already known to local HIV services, 35 were known to HIV services outside of our Trust and 5 were new diagnoses.

Conclusion

Our results confirmed our local HIV prevalence to be very high, as per the UK Health Security Agency and supports the need for HIV testing. Opt-out ED BBV screening has been a highly effective method for identifying people living with HIV who are unaware of their status.
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来源期刊
Journal of Clinical Virology
Journal of Clinical Virology 医学-病毒学
CiteScore
22.70
自引率
1.10%
发文量
149
审稿时长
24 days
期刊介绍: The Journal of Clinical Virology, an esteemed international publication, serves as the official journal for both the Pan American Society for Clinical Virology and The European Society for Clinical Virology. Dedicated to advancing the understanding of human virology in clinical settings, the Journal of Clinical Virology focuses on disseminating research papers and reviews pertaining to the clinical aspects of virology. Its scope encompasses articles discussing diagnostic methodologies and virus-induced clinical conditions, with an emphasis on practicality and relevance to clinical practice. The journal publishes on topics that include: • new diagnostic technologies • nucleic acid amplification and serologic testing • targeted and metagenomic next-generation sequencing • emerging pandemic viral threats • respiratory viruses • transplant viruses • chronic viral infections • cancer-associated viruses • gastrointestinal viruses • central nervous system viruses • one health (excludes animal health)
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