长期服用阿仑膦酸钠导致一名 36 岁女性发生非典型股骨干骨折：病例报告和文献综述。

IF 1.4 4区医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL Journal of International Medical Research Pub Date : 2024-10-01 DOI:10.1177/03000605241286650

Wenyu Duan, Maochang Qiang, Haidong Zhang, Dongming Zhou

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引用次数: 0

摘要

长期的双膦酸盐治疗与非典型或功能不全骨折有关，尤其是在股骨近端。我们观察到一例长期接受阿仑膦酸盐治疗的患者发生了非典型股骨干骨折。一名 36 岁的女性因低能量创伤后右大腿中部疼痛而入院。她服用阿仑膦酸钠已超过 15 年。X 光片显示右股骨轴骨折。患者接受了股骨近端钉抗旋转（PFNA）固定治疗。本病例凸显了对长期双膦酸盐治疗及其潜在并发症的担忧。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Long-term administration of alendronate sodium caused an atypical femoral shaft fracture in a 36-year-old woman: a case report and literature review.

Long-term bisphosphonate therapy is associated with atypical or insufficiency fractures, particularly in the proximal femur. We observed a case of an atypical femoral shaft fracture in a patient with a long-term history of alendronate therapy. A 36-year-old woman was admitted with a complaint of pain in her right mid-thigh following low-energy trauma. She had been taking alendronate for more than 15 years. X-rays indicated a fracture of the right femoral shaft. The patient was treated with proximal femoral nail antirotation (PFNA) fixation. This case highlights concerns regarding long-term bisphosphonate therapy and its potential complications.

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来源期刊

Journal of International Medical Research 医学-药学

CiteScore

3.20

自引率

0.00%

发文量

555

审稿时长

1 months

期刊介绍： _Journal of International Medical Research_ is a leading international journal for rapid publication of original medical, pre-clinical and clinical research, reviews, preliminary and pilot studies on a page charge basis. As a service to authors, every article accepted by peer review will be given a full technical edit to make papers as accessible and readable to the international medical community as rapidly as possible. Once the technical edit queries have been answered to the satisfaction of the journal, the paper will be published and made available freely to everyone under a creative commons licence. Symposium proceedings, summaries of presentations or collections of medical, pre-clinical or clinical data on a specific topic are welcome for publication as supplements. Print ISSN: 0300-0605