妇科癌症手术患者淋巴水肿及其他并发症的发生率,包括两种淋巴结清扫技术的使用。

IF 1.6 4区 医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL Lymphatic research and biology Pub Date : 2024-10-28 DOI:10.1089/lrb.2024.0084
Varol Gülseren, Mehmet Dolanbay, İsa Aykut Özdemir, Fulya Çağlı, Ertuğrul Şen, Bülent Özçelik, İbrahim Serdar Serin, Kemal Güngördük
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引用次数: 0

摘要

背景:评估淋巴结清扫(LND)技术对短期和长期并发症的影响。该回顾性研究纳入了 2020 年至 2022 年期间在我院妇科肿瘤外科门诊接受子宫切除术、输卵管切除术和盆腔 ± 腹主动脉旁 LND 治疗妇科恶性肿瘤(宫颈癌、子宫内膜癌和卵巢癌)的患者。方法和结果:在因妇科恶性肿瘤接受盆腔 LND 治疗的 147 位患者中,48 位接受了剪刀手术,99 位接受了单极烧灼手术。两组患者提取的盆腔淋巴结和主动脉旁淋巴结数量无明显差异。剪刀组和单极烧灼组的 LND 范围相当(p = 0.945)。剪刀组在术后第 2 天和第 5 天的液体引流较少(1300 [600-3100] vs 1800 [600-3400]; p = 0.038)。在主要的早期和晚期临床结果方面,各组之间的淋巴囊肿率(16.7% vs 15.2%;P = 0.494)和淋巴水肿率(18.8% vs 17.2%;P = 0.491)无显著差异。结论妇科恶性肿瘤腹膜后LND术后,早期并发症(如淋巴囊肿)和晚期并发症(如下肢淋巴水肿)在使用冷剪刀和使用单极烧灼术的手术中没有显著差异。
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Incidence of Lymphedema and Other Complications in Patients Operated on for Gynecological Cancer Including Utilization of Two Lymph Node Dissection Techniques.

Background: To assess the impact of the lymph node dissection (LND) technique on short- and long-term complications. This retrospective review included patients who underwent hysterectomy, oophorectomy, and pelvic ± para-aortic LND for gynecological malignancies (cervical, endometrial, and ovarian) from 2020 to 2022 in our Gynecological Oncology Surgery clinic. Methods and Results: Among 147 patients who underwent pelvic LND for gynecological malignancy, 48 had procedures involving scissors and 99 had procedures involving unipolar cautery. There was no significant difference in the numbers of extracted pelvic and para-aortic lymph nodes between groups. The extents of LND were comparable between the scissors and unipolar cautery groups (p = 0.945). The scissors group exhibited less fluid drainage between days 2 and 5 postoperatively (1300 [600-3100] vs 1800 [600-3400]; p = 0.038). In terms of primary early and late clinical outcomes, there were no significant differences in lymphocele (16.7% vs 15.2%; p = 0.494) and lymphedema (18.8% vs 17.2%; p = 0.491) rates between groups. Conclusions: After retroperitoneal LND for gynecological malignancy, early complications such as lymphocele and late complications such as lower extremity lymphedema did not significantly differ between procedures using cold scissors and procedures using unipolar cautery.

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来源期刊
Lymphatic research and biology
Lymphatic research and biology Medicine-Cardiology and Cardiovascular Medicine
CiteScore
3.10
自引率
7.10%
发文量
85
审稿时长
>12 weeks
期刊介绍: Lymphatic Research and Biology delivers the most current peer-reviewed advances and developments in lymphatic biology and pathology from the world’s leading biomedical investigators. The Journal provides original research from a broad range of investigative disciplines, including genetics, biochemistry and biophysics, cellular and molecular biology, physiology and pharmacology, anatomy, developmental biology, and pathology. Lymphatic Research and Biology coverage includes: -Vasculogenesis and angiogenesis -Genetics of lymphatic disorders -Human lymphatic disease, including lymphatic insufficiency and associated vascular anomalies -Physiology of intestinal fluid and protein balance -Immunosurveillance and immune cell trafficking -Tumor biology and metastasis -Pharmacology -Lymphatic imaging -Endothelial and smooth muscle cell biology -Inflammation, infection, and autoimmune disease
期刊最新文献
A Method to Improve the Accuracy for the Comparison of Consecutively Determined Upper Limb Cross-Sectional Area Profiles of Test Subjects: Impact on (Segmental) Limb Volume and Local Limb Circumference. Incidence of Lymphedema and Other Complications in Patients Operated on for Gynecological Cancer Including Utilization of Two Lymph Node Dissection Techniques. Effects of Short-Term Educational Hospitalization with Multidisciplinary Approach for Lymphedema on Limb Circumference and Quality of Life. Chylous Reflux in Pediatric Primary Lymphedema of the Lower Limbs and Genitalia: A Retrospective Study of 167 Patients. Correspondence to the Article: "Proposed Framework for Research Case Definitions of Lipedema".
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