在资源丰富的环境中志贺氏杆菌的流行病学和抗菌药耐药率。

IF 3.6 3区 医学 Q1 PATHOLOGY Pathology Pub Date : 2024-09-25 DOI:10.1016/j.pathol.2024.07.004
Samuel Baumgart, Thuy Phan, Genevieve McKew
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引用次数: 0

摘要

志贺氏菌病是一种急性腹泻疾病,通常会引起肠道功能紊乱,在全球范围内造成大量的发病和死亡。全球范围内发现的多重耐药(MDR)和广泛耐药(XDR)志贺氏菌的发病率越来越高,因此有必要定期审查当地的流行病学和耐药率,以帮助指导经验性抗生素的选择。这项对 2013 年至 2023 年期间粪便分离物的回顾性实验室研究表明,对第三代头孢菌素、阿奇霉素和环丙沙星的耐药率在上升,同时 MDR 和 XDR 分离物的总体耐药率也在上升。
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Epidemiology and antimicrobial resistance rates for Shigella species in a resource-rich setting.

Shigellosis is an acute, often dysenteric, diarrhoeal illness that is responsible for much morbidity and mortality worldwide. Increasing rates of multidrug-resistant (MDR) and extensively drug-resistant (XDR) ​Shigella species have been detected worldwide and a regular review of local epidemiological and resistance rates is necessary to help guide empirical antibiotic choice. This retrospective laboratory study of faecal isolates between 2013 and 2023 demonstrates increasing rates of resistance to third-generation cephalosporins, azithromycin and ciprofloxacin, alongside an overall increase in MDR and XDR isolates.

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来源期刊
Pathology
Pathology 医学-病理学
CiteScore
6.50
自引率
2.20%
发文量
459
审稿时长
54 days
期刊介绍: Published by Elsevier from 2016 Pathology is the official journal of the Royal College of Pathologists of Australasia (RCPA). It is committed to publishing peer-reviewed, original articles related to the science of pathology in its broadest sense, including anatomical pathology, chemical pathology and biochemistry, cytopathology, experimental pathology, forensic pathology and morbid anatomy, genetics, haematology, immunology and immunopathology, microbiology and molecular pathology.
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