通过自述症状和心血管风险评分对大师级运动员进行赛前心血管评估的价值。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-12-01 Epub Date: 2024-10-23 DOI:10.1080/14017431.2024.2418089
Jostein Grimsmo, Kristina Hermann Haugaa, Ivan Popovic, Øyvind Haugen Lie, Erik Ekker Solberg
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引用次数: 0

摘要

在耐力竞技运动中,心脏性猝死(SCD)的风险会增加。冠状动脉疾病(CAD)是导致年龄超过 35 岁的大师级运动员(MAs)发生 SCD 的最常见原因。为降低 SCD 风险,建议在参赛前进行心血管评估(PCVE),通过问卷对症状进行自我评估,并评估心血管风险分数。我们的目的是研究 PCVE 是否能预测心血管疾病风险增加或未增加的健康体检者的心血管疾病风险(通过有效的评分工具进行测量)。我们根据 PCVE 的结果对健康的 MA 进行了单点观察性队列研究,并将他们分为两组:在问卷中报告有症状和/或心血管风险评分升高的 MA 被分为症状组 (SG),而没有症状或风险评分升高的 MA 被定义为对照组 (CG)。之后,所有人员都接受了扩展检查:静息心电图、心肺运动测试和超声心动图。SG(39 人)和 CG(42 人)在基线、性别(p = 0.11)、年龄(55.0 ± 9.8 岁 vs. 51.9 ± 11.1 岁;p = 0.18)、最大摄氧量(49.8 ± 7.6 vs. 51.6 ± 7.0 ml/kg/min;p = 0.26)、静息心率(61.4 ± 12.8 vs. 60.2 ± 11.0/min;p = 0.66)、每周训练时数(7.0 ± 3.2 vs. 7.1 ± 3.1;p = 0.88)。进一步检查发现,16 名 MA(20%)患有心血管疾病:其中 12 例为 SG,4 例为 CG(P = 0.024)。PCVE的阴性预测值和特异性分别为90%和58%。通过问卷调查和心血管风险评分得出的阴性PCVE结果可能是将受试者排除在赛前筛查之外的一种策略,从而节省了资源。
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Value of preparticipation cardiovascular evaluation of master athletes by self-reported symptoms and cardiovascular risk-score.

The risk of sudden cardiac death (SCD) is increased during endurance competitive sports. Coronary artery disease (CAD) is the most common cause of SCD in master athletes ≥ 35 years old (MAs). To reduce the risk of SCD self-assessment of symptoms by questionnaire, and evaluation of cardiovascular risk-score, are recommended as pre-participation cardiovascular evaluation (PCVE). We aimed to examine whether PCVE predicts CVD in MAs with or without increased risk as measured by validated score instruments.

We performed a single-site observational cohort study of healthy MAs based on findings at PCVE. They were allocated in two different groups: those MAs with reported symptoms on the questionnaire and/or with elevated cardiovascular risk score were allocated to a symptom group (SG), while MAs with no symptoms, nor raised risk score were defined as control group (CG). Thereafter, all were examined with extended examinations: resting-ECG, cardiorespiratory exercise testing and echocardiography.

Total, 81 (18 women) MAs participated in the study. There were no differences at baseline between SG (n = 39) and CG (n = 42); sex (p = 0.11), age (55.0 ± 9.8 vs. 51.9 ± 11.1 years; p = 0.18), maximal oxygen uptake (49.8 ± 7.6 vs. 51.6 ± 7.0 ml/kg/min; p = 0.26), resting heart rate (61.4 ± 12.8 vs. 60.2 ± 11.0/min; p = 0.66), training hours/week (7.0 ± 3.2 vs. 7.1 ± 3.1; p = 0.88). After further examination, sixteen (20%) MAs were found with CVD: 12 in SG, 4 in CG (p = 0.024). The negative predictive value and specificity of the PCVE were 90% and 58%, respectively.

Negative findings on PCVE by questionnaire and cardiovascular risk-score may be a strategy to exclude subjects from preparticipation screening, thus saving resources.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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