Yue Wu , Xiao-Yan Meng , Hui-Fang Sun , Ying-Jie Zhang , Xiao-Hui Liu , Dian-Dian Wang , Dan-Hua Liu , Sen-Miao Li , Jia-Kang Li , Wen-Xiu Li , Shu-Ang Li , Pei-Pei Liu , Jian-Sheng Kang
{"title":"从一名健康女性的成纤维细胞中构建诱导多能干细胞系(CSBZZUi002-A)。","authors":"Yue Wu , Xiao-Yan Meng , Hui-Fang Sun , Ying-Jie Zhang , Xiao-Hui Liu , Dian-Dian Wang , Dan-Hua Liu , Sen-Miao Li , Jia-Kang Li , Wen-Xiu Li , Shu-Ang Li , Pei-Pei Liu , Jian-Sheng Kang","doi":"10.1016/j.scr.2024.103593","DOIUrl":null,"url":null,"abstract":"<div><div>We recruited a healthy 44-year-old female and obtained her skin fibroblasts. Subsequently, the induced pluripotent stem cell line was successfully established using non-integrated reprogramming technology. The cell line had a normal karyotype and has been confirmed to have good pluripotency through the detection of pluripotency markers and detection of teratoma formation. This cell line can serve as an effective control for studying the cellular pathological mechanisms of other specific mutations.</div></div>","PeriodicalId":21843,"journal":{"name":"Stem cell research","volume":null,"pages":null},"PeriodicalIF":0.8000,"publicationDate":"2024-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Construction of induced pluripotent stem cell line (CSBZZUi002-A) from the fibroblast cells of a healthy female\",\"authors\":\"Yue Wu , Xiao-Yan Meng , Hui-Fang Sun , Ying-Jie Zhang , Xiao-Hui Liu , Dian-Dian Wang , Dan-Hua Liu , Sen-Miao Li , Jia-Kang Li , Wen-Xiu Li , Shu-Ang Li , Pei-Pei Liu , Jian-Sheng Kang\",\"doi\":\"10.1016/j.scr.2024.103593\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>We recruited a healthy 44-year-old female and obtained her skin fibroblasts. Subsequently, the induced pluripotent stem cell line was successfully established using non-integrated reprogramming technology. The cell line had a normal karyotype and has been confirmed to have good pluripotency through the detection of pluripotency markers and detection of teratoma formation. This cell line can serve as an effective control for studying the cellular pathological mechanisms of other specific mutations.</div></div>\",\"PeriodicalId\":21843,\"journal\":{\"name\":\"Stem cell research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2024-10-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Stem cell research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1873506124002915\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"BIOTECHNOLOGY & APPLIED MICROBIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Stem cell research","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1873506124002915","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOTECHNOLOGY & APPLIED MICROBIOLOGY","Score":null,"Total":0}
Construction of induced pluripotent stem cell line (CSBZZUi002-A) from the fibroblast cells of a healthy female
We recruited a healthy 44-year-old female and obtained her skin fibroblasts. Subsequently, the induced pluripotent stem cell line was successfully established using non-integrated reprogramming technology. The cell line had a normal karyotype and has been confirmed to have good pluripotency through the detection of pluripotency markers and detection of teratoma formation. This cell line can serve as an effective control for studying the cellular pathological mechanisms of other specific mutations.
期刊介绍:
Stem Cell Research is dedicated to publishing high-quality manuscripts focusing on the biology and applications of stem cell research. Submissions to Stem Cell Research, may cover all aspects of stem cells, including embryonic stem cells, tissue-specific stem cells, cancer stem cells, developmental studies, stem cell genomes, and translational research. Stem Cell Research publishes 6 issues a year.