从一名健康女性的成纤维细胞中构建诱导多能干细胞系(CSBZZUi002-A)。

IF 0.8 4区 医学 Q4 BIOTECHNOLOGY & APPLIED MICROBIOLOGY Stem cell research Pub Date : 2024-10-20 DOI:10.1016/j.scr.2024.103593
Yue Wu , Xiao-Yan Meng , Hui-Fang Sun , Ying-Jie Zhang , Xiao-Hui Liu , Dian-Dian Wang , Dan-Hua Liu , Sen-Miao Li , Jia-Kang Li , Wen-Xiu Li , Shu-Ang Li , Pei-Pei Liu , Jian-Sheng Kang
{"title":"从一名健康女性的成纤维细胞中构建诱导多能干细胞系(CSBZZUi002-A)。","authors":"Yue Wu ,&nbsp;Xiao-Yan Meng ,&nbsp;Hui-Fang Sun ,&nbsp;Ying-Jie Zhang ,&nbsp;Xiao-Hui Liu ,&nbsp;Dian-Dian Wang ,&nbsp;Dan-Hua Liu ,&nbsp;Sen-Miao Li ,&nbsp;Jia-Kang Li ,&nbsp;Wen-Xiu Li ,&nbsp;Shu-Ang Li ,&nbsp;Pei-Pei Liu ,&nbsp;Jian-Sheng Kang","doi":"10.1016/j.scr.2024.103593","DOIUrl":null,"url":null,"abstract":"<div><div>We recruited a healthy 44-year-old female and obtained her skin fibroblasts. Subsequently, the induced pluripotent stem cell line was successfully established using non-integrated reprogramming technology. The cell line had a normal karyotype and has been confirmed to have good pluripotency through the detection of pluripotency markers and detection of teratoma formation. This cell line can serve as an effective control for studying the cellular pathological mechanisms of other specific mutations.</div></div>","PeriodicalId":21843,"journal":{"name":"Stem cell research","volume":null,"pages":null},"PeriodicalIF":0.8000,"publicationDate":"2024-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Construction of induced pluripotent stem cell line (CSBZZUi002-A) from the fibroblast cells of a healthy female\",\"authors\":\"Yue Wu ,&nbsp;Xiao-Yan Meng ,&nbsp;Hui-Fang Sun ,&nbsp;Ying-Jie Zhang ,&nbsp;Xiao-Hui Liu ,&nbsp;Dian-Dian Wang ,&nbsp;Dan-Hua Liu ,&nbsp;Sen-Miao Li ,&nbsp;Jia-Kang Li ,&nbsp;Wen-Xiu Li ,&nbsp;Shu-Ang Li ,&nbsp;Pei-Pei Liu ,&nbsp;Jian-Sheng Kang\",\"doi\":\"10.1016/j.scr.2024.103593\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>We recruited a healthy 44-year-old female and obtained her skin fibroblasts. Subsequently, the induced pluripotent stem cell line was successfully established using non-integrated reprogramming technology. The cell line had a normal karyotype and has been confirmed to have good pluripotency through the detection of pluripotency markers and detection of teratoma formation. This cell line can serve as an effective control for studying the cellular pathological mechanisms of other specific mutations.</div></div>\",\"PeriodicalId\":21843,\"journal\":{\"name\":\"Stem cell research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2024-10-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Stem cell research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1873506124002915\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"BIOTECHNOLOGY & APPLIED MICROBIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Stem cell research","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1873506124002915","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOTECHNOLOGY & APPLIED MICROBIOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

我们招募了一名 44 岁的健康女性,并获得了她的皮肤成纤维细胞。随后,我们利用非整合重编程技术成功建立了诱导多能干细胞系。该细胞系核型正常,通过检测多能性标志物和检测畸胎瘤的形成,证实其具有良好的多能性。该细胞系可作为研究其他特定突变的细胞病理机制的有效对照。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Construction of induced pluripotent stem cell line (CSBZZUi002-A) from the fibroblast cells of a healthy female
We recruited a healthy 44-year-old female and obtained her skin fibroblasts. Subsequently, the induced pluripotent stem cell line was successfully established using non-integrated reprogramming technology. The cell line had a normal karyotype and has been confirmed to have good pluripotency through the detection of pluripotency markers and detection of teratoma formation. This cell line can serve as an effective control for studying the cellular pathological mechanisms of other specific mutations.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Stem cell research
Stem cell research 生物-生物工程与应用微生物
CiteScore
2.20
自引率
8.30%
发文量
338
审稿时长
55 days
期刊介绍: Stem Cell Research is dedicated to publishing high-quality manuscripts focusing on the biology and applications of stem cell research. Submissions to Stem Cell Research, may cover all aspects of stem cells, including embryonic stem cells, tissue-specific stem cells, cancer stem cells, developmental studies, stem cell genomes, and translational research. Stem Cell Research publishes 6 issues a year.
期刊最新文献
Generation of SFTPC-mCherry knock-in reporter human embryonic stem cell line, WAe001-A-2H, using CRISPR/Cas9-based gene targeting Generation of four human induced pluripotent stem cell lines derived from patients with MPAN, subtype of NBIA, carrying the c.204_214del11 mutation in the C19orf12 gene Generation of human induced pluripotent stem cell (DMSCi001-A) line from hematopoietic stem cells of a healthy female donor Generation and characterization of two isogenic induced pluripotent stem cell lines from a young female with microcephaly carrying a compound heterozygous mutation in BUB1 gene Establishment and characterization of three human pluripotent stem cell lines from Charcot-Marie-Tooth disease Type 4B3 patients bearing mutations in MTMR5/Sbf1 gene
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1