[精原细胞瘤的分期治疗]。

IF 0.5 4区 医学 Q4 UROLOGY & NEPHROLOGY Urologie Pub Date : 2024-10-24 DOI:10.1007/s00120-024-02446-9
David Pfister, Constantin Rieger, Felix Seelemeyer, Axel Heidenreich
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引用次数: 0

摘要

睾丸生殖细胞肿瘤是一种罕见的实体瘤,主要发生在年轻男性身上。精原细胞瘤的发病率略高于非精原细胞瘤。精原细胞瘤的一个特点是对放射线敏感,因此在转移较少的肿瘤阶段可以选择放射治疗;但是,由于继发性恶性肿瘤的风险增加,指南的建议是谨慎的。在未转移的肿瘤阶段,积极监测是避免患者过度治疗的主要方法。这也是在转移负荷较低的病例中进行初级神经保留腹膜后淋巴结清扫术的原因。美国泌尿外科协会(AUA)和美国国立综合癌症网络(NCCN)的指南已经采用了这一概念,而欧洲泌尿外科协会(EAU)的指南仍将其视为一种个体方法。
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[Stage-dependent treatment of seminomas].

Germ cell neoplasms of the testis are rare solid tumors predominantly in young men. Seminomas are slightly more frequent than nonseminomatous germ cell tumors. A special feature of seminomas is that they are sensitive to radiation, so that this represents an option in tumor stages with few metastases; however, the guideline recommendation is cautious due to the increased risk of secondary malignancies. In nonmetastasized tumor stages active surveillance is the primary approach to avoid overtreatment of patients. This is also the reason for primary nerve-sparing retroperitoneal lymph node dissection in cases of a low metastasis load. This concept has already been implemented in the American Urological Association (AUA) and National Comprehensive Cancer Network (NCCN) guidelines, whereas in the European Association of Urology (EAU) guidelines it is still considered to be an individual approach.

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来源期刊
Urologie
Urologie UROLOGY & NEPHROLOGY-
CiteScore
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