[基于小样本临床指标数据构建引产预测模型]。

Yali Qin, Liping Yao, Ling Yuan, Sheng Chen
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引用次数: 0

摘要

由于临床指标的多样性和复杂性,现有方法很难建立一个全面可靠的引产(IOL)结果预测模型。本研究旨在分析与引产相关的临床指标,并基于小样本数据建立和评估预测模型。研究对象包括2023年2月至2024年1月期间在上海市第一妇婴保健院接受IOL的90名孕妇,共记录了52项临床指标。在选择临床指标特征时,采用了最大信息系数(MIC),以降低高维特征带来的过拟合风险。然后,根据 MIC 选择的特征,将基于小样本的支持向量机(SVM)模型与深度学习中基于大样本的全连接神经网络(FCNN)模型进行对比分析,并给出接收者操作特征曲线(ROC)。通过计算 MIC 分数,最终特征维度从 55 个减少到 15 个,SVM 模型的曲线下面积(AUC)从特征选择前的 0.872 提高到 0.923。模型比较结果表明,SVM 的预测性能优于 FCNN。本研究表明,SVM 能成功预测人工晶体植入术的结果,而 MIC 特征选择能有效提高模型的泛化能力,使预测结果更加稳定。本研究为预测引产结果提供了一种可靠的方法,具有潜在的临床应用价值。
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[Construction of a prediction model for induction of labor based on a small sample of clinical indicator data].

Because of the diversity and complexity of clinical indicators, it is difficult to establish a comprehensive and reliable prediction model for induction of labor (IOL) outcomes with existing methods. This study aims to analyze the clinical indicators related to IOL and to develop and evaluate a prediction model based on a small-sample of data. The study population consisted of a total of 90 pregnant women who underwent IOL between February 2023 and January 2024 at the Shanghai First Maternity and Infant Healthcare Hospital, and a total of 52 clinical indicators were recorded. Maximal information coefficient (MIC) was used to select features for clinical indicators to reduce the risk of overfitting caused by high-dimensional features. Then, based on the features selected by MIC, the support vector machine (SVM) model based on small samples was compared and analyzed with the fully connected neural network (FCNN) model based on large samples in deep learning, and the receiver operating characteristic (ROC) curve was given. By calculating the MIC score, the final feature dimension was reduced from 55 to 15, and the area under curve (AUC) of the SVM model was improved from 0.872 before feature selection to 0.923. Model comparison results showed that SVM had better prediction performance than FCNN. This study demonstrates that SVM successfully predicted IOL outcomes, and the MIC feature selection effectively improves the model's generalization ability, making the prediction results more stable. This study provides a reliable method for predicting the outcome of induced labor with potential clinical applications.

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来源期刊
生物医学工程学杂志
生物医学工程学杂志 Medicine-Medicine (all)
CiteScore
0.80
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0.00%
发文量
4868
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