柑橘物种中 NLR 基因的多样性和进化。

IF 3.6 3区 生物学 Q1 BIOLOGY Biology-Basel Pub Date : 2024-10-14 DOI:10.3390/biology13100822
Zhiwei Xiong, Wanshan Zhang, Hui Yin, Jiaxing Wan, Zhuozhuo Wu, Yuxia Gao
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引用次数: 0

摘要

NLR 基因是效应触发免疫(ETI)系统的重要组成部分,负责识别病原体和启动免疫反应。虽然许多植物物种的 NLR 基因已被广泛研究,但柑橘中 NLR 基因的多样性在很大程度上仍不为人所知。我们的分析表明,这些物种的 NLR 基因拷贝数差异很大。基因复制和重组被认为是这种多样性背后的主要驱动力。此外,水平基因转移(HGT)也是导致 A. buxifolia NLR 基因拷贝数增加的主要机制。柑橘 NLR 基因被分为四类:TIR-NBS-LRR(TNL)、CC-NBS-LRR(CNL)、RPW8-NBS-LRR(RNL)和 NL。我们的研究结果表明,TNL、RNL 和 CNL 基因起源于 NL 基因,它们获得了 TIR 和 RPW8 结构域以及 CC 基序,然后随机丢失了相应的结构域。系统进化分析表明,柑橘 NLR 基因起源于柑橘物种,并经历了适应性进化,可能在柑橘的全球定殖过程中发挥了关键作用。这项研究为了解柑橘 NLR 基因的多样性提供了重要依据,也为今后培育抗病柑橘品种的研究提供了基础数据集。
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Diversity and Evolution of NLR Genes in Citrus Species.

NLR genes are crucial components of the effector-triggered immunity (ETI) system, responsible for recognizing pathogens and initiating immune responses. Although NLR genes in many plant species have been extensively studied, the diversity of NLR genes in citrus remains largely unknown. Our analysis revealed significant variations in the copy numbers of NLR genes among these species. Gene duplication and recombination were identified as the major driving forces behind this diversity. Additionally, horizontal gene transfer (HGT) emerged as the principal mechanism responsible for the increase in NLR gene copy number in A. buxifolia. The citrus NLR genes were classified into four categories: TIR-NBS-LRR (TNL), CC-NBS-LRR (CNL), RPW8-NBS-LRR (RNL), and NL. Our findings indicate that TNL, RNL, and CNL genes originated from NL genes through the acquisition of TIR and RPW8 domains, along with CC motifs, followed by the random loss of corresponding domains. Phylogenetic analysis suggested that citrus NLR genes originated alongside the species and underwent adaptive evolution, potentially playing crucial roles in the global colonization of citrus. This study provides important insights into the diversity of citrus NLR genes and serves as a foundational dataset for future research aimed at breeding disease-resistant citrus varieties.

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来源期刊
Biology-Basel
Biology-Basel Biological Science-Biological Science
CiteScore
5.70
自引率
4.80%
发文量
1618
审稿时长
11 weeks
期刊介绍: Biology (ISSN 2079-7737) is an international, peer-reviewed, quick-refereeing open access journal of Biological Science published by MDPI online. It publishes reviews, research papers and communications in all areas of biology and at the interface of related disciplines. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. Electronic files regarding the full details of the experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material.
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