Mohammad Amin Habibi , Mohammad Sina Mirjnani , Saeed Kargar-Soleimanabad , Mohammad Taha Akbari Javar , Maryam Diyanati , Muhammad Hussain Ahmadvand , Inka K. Berglar , Adam A. Dmytriw
{"title":"NeVa 机械血栓切除装置在急性缺血性脑卒中中的安全性和有效性：系统综述与荟萃分析。","authors":"Mohammad Amin Habibi , Mohammad Sina Mirjnani , Saeed Kargar-Soleimanabad , Mohammad Taha Akbari Javar , Maryam Diyanati , Muhammad Hussain Ahmadvand , Inka K. Berglar , Adam A. Dmytriw","doi":"10.1016/j.jocn.2024.110892","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Recent favorable cohort studies on endovascular therapy for ischemic stroke have predominantly utilized NeVa thrombectomy (NeVa<sup>TM)</sup> stent retrievers. We carried out a systematic review and <em>meta</em>-analysis to investigate the efficacy and safety of this second-generation stent retriever in acute ischemic stroke patients.</div></div><div><h3>Method</h3><div>We conducted the study according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The electronic databases of PubMed, Embase, and Scopus were searched until 26 November 2023 and was updated on August 1, 2024.</div></div><div><h3>Results</h3><div>This <em>meta</em>-analysis systematically investigated 11 studies with a total of 805 patients suffering from ischemic stroke. The mean age of participants across the studies ranged from 65 to 77 years with a male preponderance of 50.16 %. While ten studies reported on the etiology of strokes, some studies reported the risk factors such as hypertension, dyslipidemia, diabetes, history of coronary artery disease, and previous stroke. The results of our study indicate that the all-hemorrhagic complications rate was 0.32 (95 %CI: 0.18–0.45), while the complete arterial recanalization rate was 0.76 [95 %CI: 0.49–1.04]. The overall recanalization rate was found to be 0.97 [95 %CI: 0.94–1.00]. Moreover, the postoperative hemorrhage rate was 0.28 [95 %CI: 0.14–0.41], while the repeated re-thrombosis rate was 0.01 [95 %CI: −0.01–0.03]. Lastly, the vasospasm rate was calculated to be 0.09 [95 %CI: −0.03–0.21].</div></div><div><h3>Conclusion</h3><div>NeVa™ is a safe option capable of achieving a high rate of recanalization and functional independence.</div><div>Abbreviations: PRISMA, Preferred Reporting Items for Systematic Reviews and Meta-Analyses; PROSPERO, International Prospective Register of Systematic Reviews; NeVa™, NeVa Thrombectomy; ICH, Intracranial Hemorrhage; mTICI, modified Thrombolysis in Cerebral Infarction; mRS, modified Rankin Scale; ACA, Anterior Cerebral Artery; MCA, Middle Cerebral Artery; PCA, Posterior Cerebral Artery; ICA, Internal Carotid Artery; NIHSS, National Institutes of Health Stroke Scale.</div></div>","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":"130 ","pages":"Article 110892"},"PeriodicalIF":1.9000,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The safety and efficacy of NeVa mechanical thrombectomy device in acute ischemic stroke: A systematic review and meta-analysis\",\"authors\":\"Mohammad Amin Habibi , Mohammad Sina Mirjnani , Saeed Kargar-Soleimanabad , Mohammad Taha Akbari Javar , Maryam Diyanati , Muhammad Hussain Ahmadvand , Inka K. Berglar , Adam A. Dmytriw\",\"doi\":\"10.1016/j.jocn.2024.110892\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>Recent favorable cohort studies on endovascular therapy for ischemic stroke have predominantly utilized NeVa thrombectomy (NeVa<sup>TM)</sup> stent retrievers. We carried out a systematic review and <em>meta</em>-analysis to investigate the efficacy and safety of this second-generation stent retriever in acute ischemic stroke patients.</div></div><div><h3>Method</h3><div>We conducted the study according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The electronic databases of PubMed, Embase, and Scopus were searched until 26 November 2023 and was updated on August 1, 2024.</div></div><div><h3>Results</h3><div>This <em>meta</em>-analysis systematically investigated 11 studies with a total of 805 patients suffering from ischemic stroke. The mean age of participants across the studies ranged from 65 to 77 years with a male preponderance of 50.16 %. While ten studies reported on the etiology of strokes, some studies reported the risk factors such as hypertension, dyslipidemia, diabetes, history of coronary artery disease, and previous stroke. The results of our study indicate that the all-hemorrhagic complications rate was 0.32 (95 %CI: 0.18–0.45), while the complete arterial recanalization rate was 0.76 [95 %CI: 0.49–1.04]. The overall recanalization rate was found to be 0.97 [95 %CI: 0.94–1.00]. Moreover, the postoperative hemorrhage rate was 0.28 [95 %CI: 0.14–0.41], while the repeated re-thrombosis rate was 0.01 [95 %CI: −0.01–0.03]. 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The safety and efficacy of NeVa mechanical thrombectomy device in acute ischemic stroke: A systematic review and meta-analysis
Background
Recent favorable cohort studies on endovascular therapy for ischemic stroke have predominantly utilized NeVa thrombectomy (NeVaTM) stent retrievers. We carried out a systematic review and meta-analysis to investigate the efficacy and safety of this second-generation stent retriever in acute ischemic stroke patients.
Method
We conducted the study according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The electronic databases of PubMed, Embase, and Scopus were searched until 26 November 2023 and was updated on August 1, 2024.
Results
This meta-analysis systematically investigated 11 studies with a total of 805 patients suffering from ischemic stroke. The mean age of participants across the studies ranged from 65 to 77 years with a male preponderance of 50.16 %. While ten studies reported on the etiology of strokes, some studies reported the risk factors such as hypertension, dyslipidemia, diabetes, history of coronary artery disease, and previous stroke. The results of our study indicate that the all-hemorrhagic complications rate was 0.32 (95 %CI: 0.18–0.45), while the complete arterial recanalization rate was 0.76 [95 %CI: 0.49–1.04]. The overall recanalization rate was found to be 0.97 [95 %CI: 0.94–1.00]. Moreover, the postoperative hemorrhage rate was 0.28 [95 %CI: 0.14–0.41], while the repeated re-thrombosis rate was 0.01 [95 %CI: −0.01–0.03]. Lastly, the vasospasm rate was calculated to be 0.09 [95 %CI: −0.03–0.21].
Conclusion
NeVa™ is a safe option capable of achieving a high rate of recanalization and functional independence.
Abbreviations: PRISMA, Preferred Reporting Items for Systematic Reviews and Meta-Analyses; PROSPERO, International Prospective Register of Systematic Reviews; NeVa™, NeVa Thrombectomy; ICH, Intracranial Hemorrhage; mTICI, modified Thrombolysis in Cerebral Infarction; mRS, modified Rankin Scale; ACA, Anterior Cerebral Artery; MCA, Middle Cerebral Artery; PCA, Posterior Cerebral Artery; ICA, Internal Carotid Artery; NIHSS, National Institutes of Health Stroke Scale.
期刊介绍：
This International journal, Journal of Clinical Neuroscience, publishes articles on clinical neurosurgery and neurology and the related neurosciences such as neuro-pathology, neuro-radiology, neuro-ophthalmology and neuro-physiology.
The journal has a broad International perspective, and emphasises the advances occurring in Asia, the Pacific Rim region, Europe and North America. The Journal acts as a focus for publication of major clinical and laboratory research, as well as publishing solicited manuscripts on specific subjects from experts, case reports and other information of interest to clinicians working in the clinical neurosciences.
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