在寻求人工流产护理和避孕服务的人群中,报告荷尔蒙避孕药的副作用。

IF 3.4 3区 医学 Q1 FAMILY STUDIES BMJ Sexual & Reproductive Health Pub Date : 2024-10-29 DOI:10.1136/bmjsrh-2024-202442
Karoliina Jaskari, Aydin Tekay, Tuire Helene Saloranta, Riina Korjamo, Oskari Heikinheimo, Frida Gyllenberg
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引用次数: 0

摘要

介绍:我们旨在描述和比较寻求人工流产护理或避孕服务的生殖保健用户中与使用激素避孕药相关的主观副作用的发生率:这项子研究源于之前报道的一项横断面调查,该调查涉及芬兰赫尔辛基大都会地区的 1006 名公共生殖保健服务使用者。我们纳入了所有 813 名有激素避孕史的受访者(人工流产护理的平均年龄为 27 岁,IQR 为 24-33 岁;避孕服务的平均年龄为 24 岁,IQR 为 19-30 岁)。研究遵循 STROBE 指南:结果:共有 400 名受访者寻求人工流产护理,413 名受访者寻求避孕服务(咨询、处方更新、症状和/或对避孕方法不满意)。两组受访者使用最多的避孕方法都是复方口服避孕药和纯孕激素避孕药。与寻求避孕服务的受访者相比,寻求人工流产护理的受访者更常报告与避孕相关的体重变化、性相关问题、情绪变化和痤疮(P 值结论:与使用激素避孕药有关的情绪变化是所有受访者中最常报告的副作用。这些发现表明,有必要就与情绪有关的副作用提供个性化咨询,因为情绪变化可能会导致更高的停药率。
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Reported side effects from hormonal contraceptives among those seeking abortion care versus contraceptive services.

Introduction: We aim to describe and compare the prevalence of subjective side effects associated with hormonal contraceptive use among reproductive healthcare users seeking either abortion care or contraceptive services.

Methods: This substudy derives from a previously reported cross-sectional survey involving 1006 users of public reproductive healthcare services in the Helsinki metropolitan area in Finland. We included all 813 respondents with a history of hormonal contraceptive use (mean age 27 years, IQR 24-33 for abortion care; 24 years, IQR 19-30 for contraceptive services). The study followed STROBE guidelines.

Results: Altogether 400 respondents sought abortion care, while 413 sought contraceptive services (counselling, prescription renewal, symptoms and/or dissatisfaction with their contraceptive method). Combined oral contraceptives and progestin-only pills were the most used methods in both groups. Respondents seeking abortion care reported contraception-associated weight changes, sex-related problems, mood changes, and acne more frequently than those seeking contraceptive services (p-value<0.05 for all). Some 52% of respondents seeking abortion care reported mood changes compared with 29% of those seeking contraceptive services, with a crude OR of 2.7 (95% CI 2.00 to 3.57). After adjustment, the OR for reporting mood changes among respondents seeking abortion care was 1.5 (95% CI 1.05 to 2.23).

Conclusions: Mood changes associated with hormonal contraceptive use were the most frequently reported side effect among all respondents. These findings suggest a need for individualised counselling on mood-related side effects as mood changes may contribute to higher discontinuation rates.

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来源期刊
BMJ Sexual & Reproductive Health
BMJ Sexual & Reproductive Health Medicine-Reproductive Medicine
CiteScore
5.10
自引率
6.10%
发文量
38
期刊介绍: BMJ Sexual & Reproductive Health is a multiprofessional journal that promotes sexual and reproductive health and wellbeing, and best contraceptive practice, worldwide. It publishes research, debate and comment to inform policy and practice, and recognises the importance of professional-patient partnership.
期刊最新文献
Shifting discourses, changing interests? How the language of sexual and reproductive health has evolved in the past 50 years. "That's not how abortions happen": a qualitative study exploring how young adults navigate abortion misinformation in the post-Roe era. Attitudes towards the regulation and provision of abortion among healthcare professionals in Britain: cross-sectional survey data from the SACHA Study. Reported side effects from hormonal contraceptives among those seeking abortion care versus contraceptive services. The post-Roe potential of mifepristone and misoprostol in the United States.
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