复发性转移性宫颈癌的系统治疗进展。

IF 1 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL British journal of hospital medicine Pub Date : 2024-10-30 Epub Date: 2024-10-14 DOI:10.12968/hmed.2024.0279
Guohui Kang, Weimin Du, Shu Zeng, Xiaomei Wu
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引用次数: 0

摘要

宫颈癌仍然是全球妇女,尤其是欠发达国家妇女因癌症死亡的主要原因。尽管标准疗法在不断进步,但复发转移性宫颈癌患者的预后仍然很差,可供选择的治疗方案也很有限。本研究旨在评估新出现的治疗方法(包括免疫疗法、靶向药物和化疗)的疗效和安全性。我们对最近的文献和临床试验进行了回顾,强调了系统治疗转移性宫颈癌所取得的重大进展。虽然每种治疗方法都有其优势和局限性,但综合数据表明,随着这些新型疗法的采用,患者的治疗效果呈改善趋势。然而,患者反应的异质性凸显了个性化治疗策略的必要性。总之,医疗技术的改进和定制治疗方法的采用使复发性转移性宫颈癌的治疗取得了令人鼓舞的进展。为了进一步加强对患者的治疗,迫切需要更广泛的临床试验数据和更有效的个性化治疗方案。本研究旨在通过全面分析当前的治疗策略和确定未来的研究领域,为这项工作做出贡献。
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Advances in systemic treatment for recurrent metastatic cervical cancer.

Cervical cancer remains a leading cause of cancer-related mortality among women worldwide, particularly in underdeveloped nations. Despite advances in standard therapies, patients with recurrent metastatic cervical cancer face a poor prognosis and limited treatment options. This study aims to evaluate the efficacy and safety of emerging therapeutic approaches in managing this challenging condition, including immunotherapy, targeted medicines, and chemotherapy. Our review of recent literature and clinical trials highlights the significant progress made in the systematic treatment of metastatic cervical cancer. While each treatment modality has its strengths and limitations, the collective data suggest a trend towards improved patient outcomes with the adoption of these novel therapies. However, the heterogeneity of patient responses underscores the need for personalised treatment strategies. In conclusion, improvements in medical technology and the adoption of tailored treatment approaches have led to promising advancements in the management of recurrent metastatic cervical cancer. To further enhance patient care, there is an urgent need for more extensive clinical trial data and the development of more efficient personalised treatment plans. This study aims to contribute to this effort by comprehensively analysing current therapeutic strategies and identifying areas for future research.

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来源期刊
British journal of hospital medicine
British journal of hospital medicine 医学-医学:内科
CiteScore
1.50
自引率
0.00%
发文量
176
审稿时长
4-8 weeks
期刊介绍: British Journal of Hospital Medicine was established in 1966, and is still true to its origins: a monthly, peer-reviewed, multidisciplinary review journal for hospital doctors and doctors in training. The journal publishes an authoritative mix of clinical reviews, education and training updates, quality improvement projects and case reports, and book reviews from recognized leaders in the profession. The Core Training for Doctors section provides clinical information in an easily accessible format for doctors in training. British Journal of Hospital Medicine is an invaluable resource for hospital doctors at all stages of their career. The journal is indexed on Medline, CINAHL, the Sociedad Iberoamericana de Información Científica and Scopus.
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