以处方促变革--在医院中更安全地使用抗菌药物。

IF 3.6 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Clinical Medicine Pub Date : 2024-10-29 DOI:10.1016/j.clinme.2024.100261
Sean O'Gorman, Arthur Jackson, Karen Fitzmaurice
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引用次数: 0

摘要

世卫组织指出,AMR 是人类面临的最大健康威胁之一,造成了严重的发病率和死亡率,对弱势群体患者的影响尤为严重。世卫组织于 2015 年制定了全球行动计划,大多数国家都制定了自己的国家计划,采取 "全系统一健康 "的方法,包括感染预防和通过管理计划和诊断优化抗菌药物的使用。在医院中,抗菌药物是一些最常用的处方药,这对新出现的耐药性造成了巨大的选择压力。医院抗菌药物管理(AMS)包括一系列结构化干预措施,旨在优化治疗效果,同时限制危害。抗菌药物管理是有效的,其好处已得到证实,如改善疗效和减少耐药性在医院中的传播。本文强调了抗菌药物处方的关键原则,并重点介绍了最近的一些证据,其中一些证据已经改变了实践。
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Prescribing for change - safer antimicrobial use in hospitals.

The World Health Organization (WHO) has stated that antimicrobial resistance is one of the greatest health threats facing humanity and is responsible for significant morbidity and mortality, with a disproportionate impact on vulnerable groups of patients. The WHO set out its global action plan in 2015 and most countries have their own national plans, which take a whole system One Health approach that includes infection prevention and optimising the use of antimicrobials through stewardship programmes and diagnostics. In hospitals, antimicrobials are some of the most commonly prescribed medications, creating significant selection pressure for emerging resistance. Antimicrobial stewardship (AMS) in hospitals comprises a set of structured interventions that seek to optimise the benefits of treatments while limiting the harms. AMS is effective and has proven benefits such as improved outcomes and reduced spread of resistance in hospitals. This paper highlights key principles for antimicrobial prescribing and highlights recent evidence, some of which has been practice changing.

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来源期刊
Clinical Medicine
Clinical Medicine 医学-医学:内科
CiteScore
7.20
自引率
0.00%
发文量
0
审稿时长
6-12 weeks
期刊介绍: Clinical Medicine is aimed at practising physicians in the UK and overseas and has relevance to all those managing or working within the healthcare sector. Available in print and online, the journal seeks to encourage high standards of medical care by promoting good clinical practice through original research, review and comment. The journal also includes a dedicated continuing medical education (CME) section in each issue. This presents the latest advances in a chosen specialty, with self-assessment questions at the end of each topic enabling CPD accreditation to be acquired. ISSN: 1470-2118 E-ISSN: 1473-4893 Frequency: 6 issues per year
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