机器人单吻合器十二指肠-回肠旁路术与袖状胃切除术(SADI-S)治疗病态肥胖症:系统综述。

IF 1.8 4区 医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL In vivo Pub Date : 2024-11-01 DOI:10.21873/invivo.13733
Theodoros Kozonis, Kyriacos Evangelou, Christos Damaskos, Nikolaos Garmpis, Gerasimos Tsourouflis, Stylianos Kykalos, Emmanouil Kritsotakis, Christina Kontopoulou, Theodosios Theodosopoulos, Dimitrios Dimitroulis
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引用次数: 0

摘要

背景/目的:自 1975 年以来,全球肥胖症发病率急剧上升,给全世界带来了巨大的健康和经济挑战。机器人辅助单吻合十二指肠-回肠旁路袖状胃切除术(SADI-S)已成为治疗病态肥胖的一种很有前景的外科干预方法,与传统的腹腔镜方法相比,SADI-S在精确性、安全性和恢复效果方面具有潜在的优势。本研究旨在评估机器人辅助 SADI-S 的有效性和安全性,重点关注围手术期和术后结果,包括术中并发症、手术时间、转换率、死亡率、住院时间、体重减轻和术后并发症:在PubMed、Scopus和Cochrane图书馆进行了全面的文献检索,坚持纳入和排除标准,重点关注接受机器人SADI-S手术的肥胖成人。最终纳入了 2015 年至 2024 年间发表的 7 项研究,涉及 204 名患者:分析结果显示,术中并发症发生率低(0.49%),无死亡率,手术时间长短不一(138 到 205.7 分钟)。中位住院时间从 2 天到 6.7 天不等,再入院率极低。6.37%的患者出现了术后并发症,但没有晚期并发症(超过30天)的报道。值得注意的是,术后体重明显减轻,随访24个月时,平均超重率(EWL)高达113.74%:结论:机器人辅助 SADI-S 具有良好的安全性和可喜的减重效果,突出了其作为病态肥胖症初治或复治疗法的潜力。与传统腹腔镜方法相比,还需要进一步的研究,包括随机对照试验,以确定其长期疗效和成本效益。
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Robotic Single Anastomosis Duodenal-ileal Bypass With Sleeve Gastrectomy (SADI-S) for Morbid Obesity: A Systematic Review.

Background/aim: The global obesity epidemic has seen a dramatic increase in prevalence since 1975, posing significant health and economic challenges worldwide. Robotic-assisted single anastomosis duodenal-ileal bypass with sleeve gastrectomy (SADI-S) has emerged as a promising surgical intervention for morbid obesity, offering potential advantages over traditional laparoscopic approaches in terms of precision, safety, and recovery outcomes. This study aimed to evaluate the efficacy and safety of robotic-assisted SADI-S, focusing on perioperative and postoperative outcomes including intraoperative complications, operative time, conversion rates, mortality, length of hospital stay, weight loss, and postoperative complications.

Materials and methods: A comprehensive literature search was conducted on PubMed, Scopus, and Cochrane Library, adhering to inclusion and exclusion criteria focused on obese adult humans undergoing robotic SADI-S. Seven studies, published between 2015 and 2024, involving 204 patients, were ultimately included for analysis.

Results: The analysis revealed a low rate of intraoperative complications (0.49%), no mortality, and varied operative times (138 to 205.7 min). The median hospital stay ranged from 2 to 6.7 days, with minimal readmission rates. Postoperative complications occurred in 6.37% of patients, but no late complications (>30 days) were reported. Notably, significant weight loss outcomes were documented, with mean excess weight loss (EWL) up to 113.74% at 24 months follow-up.

Conclusion: Robotic-assisted SADI-S demonstrates a favourable safety profile with promising weight loss outcomes, highlighting its potential as a primary or revisional treatment for morbid obesity. Further research, including randomized controlled trials, is needed to establish its long-term efficacy and cost-effectiveness compared to traditional laparoscopic methods.

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来源期刊
In vivo
In vivo 医学-医学:研究与实验
CiteScore
4.20
自引率
4.30%
发文量
330
审稿时长
3-8 weeks
期刊介绍: IN VIVO is an international peer-reviewed journal designed to bring together original high quality works and reviews on experimental and clinical biomedical research within the frames of physiology, pathology and disease management. The topics of IN VIVO include: 1. Experimental development and application of new diagnostic and therapeutic procedures; 2. Pharmacological and toxicological evaluation of new drugs, drug combinations and drug delivery systems; 3. Clinical trials; 4. Development and characterization of models of biomedical research; 5. Cancer diagnosis and treatment; 6. Immunotherapy and vaccines; 7. Radiotherapy, Imaging; 8. Tissue engineering, Regenerative medicine; 9. Carcinogenesis.
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