与保守治疗相比,手术治疗首次髌骨脱位的儿科患者可降低再脱位率:系统回顾和荟萃分析。

IF 4.3 3区 材料科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC ACS Applied Electronic Materials Pub Date : 2024-10-30 DOI:10.1002/ksa.12524
Benjamin Blackman, Joshua Dworsky-Fried, Dan Cohen, David Slawaska-Eng, Lauren Gyemi, Nicole Simunovic, Devin Peterson, Olufemi R Ayeni, Darren de Sa
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引用次数: 0

摘要

目的:本研究旨在评估对首次髌骨脱位的儿科患者进行早期手术干预是否优于保守治疗。我们假设,与保守治疗相比,手术干预将导致较低的再脱位率:方法:检索了从开始到 2024 年 3 月 14 日的三个在线数据库(PubMed、MEDLINE 和 EMBASE),以确定调查儿科患者急性首次髌骨脱位治疗方案的研究。研究人员摘录了与患者人口统计学、患者管理、再脱位率以及评估功能的 Kujala 评分相关的数据。通过加权平均数和荟萃分析来比较再脱位率和 Kujala 评分。纳入研究的质量采用非随机研究的方法学指数标准和随机对照试验(RCT)的 ROB2 工具进行评估:本综述共纳入了 11 项研究和 761 名患者。在平均 53.2 个月(12-168 个月)的随访中,手术组术后再脱位的加权平均综合发生率为 25.1%,而保守组为 46.4%。重新脱位的相对风险 (RR) 为 0.82(95% 置信区间 [CI]:0.65-1.04,I2 = 0%,P = 0.11),手术治疗优于保守治疗。对最近进行的两项 RCT(共 110 例患者)进行的亚组荟萃分析表明,重新脱位的 RR 为 0.53(95% CI:0.31-0.91,I2 = 0%,p = 0.02),手术治疗更胜一筹。三项比较研究的Kujala评分显示平均差异为-2.7(95% CI:-6.1至0.68,I2 = 0%,P = 0.12),倾向于保守治疗。在131名接受内侧髌股韧带重建术(MPFLR)的患者中,加权平均再脱位率为3.1%,而在203名接受其他手术治疗(如外侧松解和内侧嵌顿术、Roux-Goldwaith术和MPFL修复术)的患者中,再脱位率为39.4%。此外,保守治疗组的并发症发生率为0.9%,而手术组的并发症发生率为2.9%:结论:与保守治疗相比,手术治疗首次髌骨脱位(尤其是 MPFLR)可能更有利于降低再脱位率。Kujala评分无明显差异:证据级别:IV级。
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Surgical management of first-time patellar dislocations in paediatric patients may lower rates of redislocation compared to conservative management: A systematic review and meta-analysis.

Purpose: The purpose of this study is to assess whether early surgical intervention for first-time patellar dislocations in paediatric patients is superior to conservative management. We hypothesized that surgical intervention would lead to lower redislocation rates compared to conservative treatment.

Methods: Three online databases (PubMed, MEDLINE and EMBASE) were searched from inception to 14 March 2024 to identify studies investigating the management options for acute first-time patellar dislocations in paediatric patients. Data pertaining to patient demographics, patient management, redislocation rates and Kujala scores, evaluating function, were abstracted. Weighted means and meta-analyses were conducted to compare rates of redislocation, as well as Kujala scores. The quality of included studies was assessed using the methodological index for non-randomized studies criteria for non-randomized studies and the ROB2 tool for randomized controlled trials (RCTs).

Results: A total of 11 studies and 761 patients were included in this review. The weighted mean post-operative combined rates of redislocation in the surgical group was 25.1%, compared to 46.4% in the conservative group at a mean follow-up of 53.2 months (12-168). The relative risk (RR) of redislocation was 0.82 (95% confidence interval [CI]: 0.65-1.04, I2 = 0%, p = 0.11), favouring surgery compared to conservative management. A subgroup meta-analysis of two recent RCTs with 110 patients demonstrated an RR of redislocation of 0.53 (95% CI: 0.31-0.91, I2 = 0%, p = 0.02), favouring surgery. Kujala scores among three comparative studies showed a mean difference of -2.7 (95% CI: -6.1 to 0.68, I2 = 0%, p = 0.12), favouring conservative treatment. The weighted mean redislocation rate in 131 patients undergoing medial patellofemoral ligament reconstruction (MPFLR) was 3.1%, compared to 39.4% in 203 patients undergoing other surgical procedures, such as lateral release and medial imbrication, Roux-Goldwaith and MPFL repair. Furthermore, the conservative groups experienced a complication rate of 0.9% compared to 2.9% across the surgical groups.

Conclusion: Surgical management for first-time patellar dislocations in a paediatric population, particularly MPFLR, may be more beneficial in lowering redislocation rates than conservative management. No significant differences in Kujala scores were found.

Level of evidence: Level IV.

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