美国退伍军人中阈值以下创伤后应激障碍的患病率、相关因素和负担。

IF 4.5 2区 医学 Q1 PSYCHIATRY Journal of Clinical Psychiatry Pub Date : 2024-10-23 DOI:10.4088/JCP.24m15465
Ian C Fischer, Peter J Na, Ilan Harpaz-Rotem, Brian P Marx, Robert H Pietrzak
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引用次数: 0

摘要

目标:根据最近提出的阈下创伤后应激障碍(PTSD)的工作病例定义,对美国退伍军人中的阈下创伤后应激障碍(PTSD)进行最新估计,并确定阈下创伤后应激障碍与完全创伤后应激障碍的社会人口、精神和功能相关性:对具有全国代表性的美国退伍军人样本数据进行了分析。可能的终生阈下创伤后应激障碍被定义为:自我报告认可潜在创伤事件(标准 A);任何 2 或 3 个创伤后应激障碍症状群(标准 B-E);症状持续时间超过 1 个月(标准 F);创伤后应激障碍症状相关的痛苦或功能障碍(标准 G):终生完全创伤后应激障碍患病率为 8.4%(95% CI,7.2%-9.7%),亚阈值创伤后应激障碍患病率为 3.9%(95% CI,3.2%-4.8%)。与没有创伤后应激障碍的退伍军人相比,阈下创伤后应激障碍与当前和终生精神障碍和临床问题的发生几率间歇性升高有关(调整后的几率比[OR]为:当前酗酒障碍 1.7,终生重度抑郁障碍 [MDD]3.3)。完全创伤后应激障碍与大多数结果相关的几率更大(调整后的几率比从当前药物使用障碍的 1.7 到终生重度抑郁障碍的 11.1 不等)。与未患创伤后应激障碍和患完全创伤后应激障碍的退伍军人相比,患阈下创伤后应激障碍的退伍军人在精神、社会心理和认知功能方面都有中等程度的下降:阈下创伤后应激障碍在美国退伍军人中很普遍,并与相当大的精神和功能困扰/损害有关。努力识别和治疗阈下创伤后应激障碍退伍军人可能会改善这一人群的心理健康和功能。
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Prevalence, Correlates, and Burden of Subthreshold PTSD in US Veterans.

Objectives: To provide an up-to-date estimate of subthreshold posttraumatic stress disorder (PTSD) in US military veterans based on a recently proposed working case definition of subthreshold PTSD and identify sociodemographic, psychiatric, and functional correlates of subthreshold PTSD relative to full PTSD.

Methods: Data were analyzed from a nationally representative sample of US veterans. Probable lifetime subthreshold PTSD was operationalized as self reported endorsement of a potentially traumatic event (Criterion A); any 2 or 3 PTSD symptom clusters (Criteria B-E); symptom duration of more than 1 month (Criterion F); and PTSD symptom-related distress or functional impairment (Criterion G).

Results: The prevalence of lifetime full PTSD was 8.4% (95% CI, 7.2%-9.7%) and the prevalence of subthreshold PTSD was 3.9% (95% CI, 3.2%-4.8%). Subthreshold PTSD was associated with intermediately elevated odds of current and lifetime psychiatric disorders and clinical problems relative to veterans with no PTSD (adjusted odds ratios [OR] ranged from 1.7 for current alcohol use disorder and 3.3 for lifetime major depressive disorder [MDD]). Full PTSD was associated with even greater odds for most outcomes (OR ranges from 1.7 for current drug use disorder to 11.1 for lifetime MDD). Veterans with subthreshold PTSD reported intermediate-level reductions in mental, psychosocial, and cognitive functioning relative to veterans with no PTSD and full PTSD.

Conclusions: Subthreshold PTSD is prevalent and associated with considerable psychiatric and functional distress/impairment among US veterans. Efforts to identify and treat veterans with subthreshold PTSD may lead to improvements in mental health and functioning in this population.

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来源期刊
Journal of Clinical Psychiatry
Journal of Clinical Psychiatry 医学-精神病学
CiteScore
7.40
自引率
1.90%
发文量
0
审稿时长
3-8 weeks
期刊介绍: For over 75 years, The Journal of Clinical Psychiatry has been a leading source of peer-reviewed articles offering the latest information on mental health topics to psychiatrists and other medical professionals.The Journal of Clinical Psychiatry is the leading psychiatric resource for clinical information and covers disorders including depression, bipolar disorder, schizophrenia, anxiety, addiction, posttraumatic stress disorder, and attention-deficit/hyperactivity disorder while exploring the newest advances in diagnosis and treatment.
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