七名家庭成员在觅食野葱后发生急性死亡骆驼蓬(Toxicoscordion venenosum)植物中毒。

IF 2.7 3区 医学 Q1 EMERGENCY MEDICINE American Journal of Emergency Medicine Pub Date : 2024-10-17 DOI:10.1016/j.ajem.2024.10.027
Kevin A Padrez, Benjamin L Stix, Cody A Cunningham, Abdelmohaymin Abdalla, Marisa Oishi, Vanessa Cardy, Sean Patrick Nordt
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引用次数: 0

摘要

背景:无意摄入植物和植物中毒很常见。一般来说,这些误食没有症状或症状轻微。毒性增加通常与觅食植物时被错误地认定为可食用植物有关。我们介绍了一个系列病例,七个家庭成员在觅食野葱(Allium canadense)时被误认为是可食用的植物,导致疑似死亡野茶(又称草甸死亡野茶,Toxicoscordion venenosum)中毒:病例系列:五名儿童和两名成人在食用了疑似死亡野茶(Toxicoscordion venenosum)的球茎后到急诊科就诊。症状在 30 至 60 分钟内开始出现,包括恶心、呕吐和腹痛。随后出现心动过缓和低血压,这与α受体阻滞、钠离子通道激活以及毒素引起的迷走神经活动增强导致的死亡骆驼中毒症状一致。所有患者都需要入住重症监护室。六名患者仅接受了支持性护理,两名患者需要血管加压支持。一名 89 岁的女性患者出现宽复律心动过速,接受了胺碘酮治疗。所有患者均在 24 小时内缓解了毒性反应,并出院回家。急诊医生为什么要注意这一点?食源性疾病是一种常见病,主要表现为多人食用同一食物后出现症状和体征。将有毒植物误认为可食用与中毒症状和体征的急性发作有关。通常被认为是可食用的野葱(Allium canadense)的死亡荠(Toxicoscordion venenosum)的毒素是独特的,因为这些毒素可引起胃肠道反应(如恶心、呕吐、腹泻)和心血管反应(如心动过缓、低血压),仅靠支持疗法(如晶体液)往往难以奏效,可能需要使用阿托品和血管加压药。
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Acute death Camas (Toxicoscordion venenosum) plant poisoning in seven family members following foraging for wild onions.

Background: Unintentional plant ingestions and poisoning are common. Generally, these ingestions are asymptomatic or minimally symptomatic. Increased toxicity is often associated with the foraging for plants incorrectly identified as edible plants. We present a case series of seven family members poisoned by suspected Death Camas, also known as Meadow Death Camas, (Toxicoscordion venenosum), when the plant was misidentified as edible while foraging for Wild Onion (Allium canadense).

Case series: Five children and two adults presented to the emergency department after eating bulbs of suspected Death Camas (Toxicoscordion venenosum). Symptoms began within 30 to 60 min including nausea, vomiting, and abdominal pain. This was followed by bradycardia and hypotension consistent with Death Camas poisoning from alpha blockade, sodium channel activation, and increased vagal activity from the toxins. All of the patients required admission to the intensive care unit. Six patients were treated with supportive care alone and two patients required vasopressor support. An 89-year-old female developed a wide complex tachycardia and was treated with amiodarone. All patients had resolution of toxicity within 24 h and were discharged to home. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Foodborne illness is a common presentation highlighted by signs and symptoms manifesting in multiple people eating the same meal. The misidentification of toxic plants as edible is associated with acute onset of signs and symptoms of toxicity. The toxins associated with Death Camas (Toxicoscordion venenosum), commonly thought to be edible Wild Onion (Allium canadense), are unique as these can cause gastrointestinal effects (e.g., nausea, vomiting, diarrhea), and cardiovascular effects (e.g., bradycardia, hypotension), which are often refractory to supportive therapy alone (e.g., crystalloid fluids), and can require atropine and vasopressors.

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来源期刊
CiteScore
6.00
自引率
5.60%
发文量
730
审稿时长
42 days
期刊介绍: A distinctive blend of practicality and scholarliness makes the American Journal of Emergency Medicine a key source for information on emergency medical care. Covering all activities concerned with emergency medicine, it is the journal to turn to for information to help increase the ability to understand, recognize and treat emergency conditions. Issues contain clinical articles, case reports, review articles, editorials, international notes, book reviews and more.
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