马来西亚患有膝关节疼痛的老年人患肌肉疏松症、住院和死亡的风险:五年随访研究。

IF 1.4 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Asia-Pacific Journal of Public Health Pub Date : 2024-10-29 DOI:10.1177/10105395241292173
Chiaw Lee Chiew, Sumaiyah Mat, Shahrul Bahyah Kamaruzzaman, Ai-Vyrn Chin, Maw Pin Tan
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引用次数: 0

摘要

本研究探讨了膝关节疼痛和膝关节骨关节炎(OA)症状与肌肉疏松症、住院和死亡风险之间的纵向关系。研究采用了马来西亚老年人纵向研究(MELoR)的数据。膝关节疼痛和膝关节OA症状是在2013年至2015年期间的基线时确定的,而肌肉疏松症是在2019年通过电话访问使用SARC-F确定的。通过询问参与者 "自加入 MELoR 研究以来,您是否入院治疗过?"来确定住院状态。死亡登记数据来自国家登记部门。共纳入了 577 人的数据,平均年龄 (SD) = 68.214 (7.095),年龄范围 = 54 至 97 岁,基线女性占 55.5%。在对混杂因素进行调整后,膝关节疼痛和膝关节 OA 症状与随访时可能出现的肌肉疏松症的风险增加有关,几率比(95% 置信区间)分别为 2.71 [1.61, 4.58] 和 2.73 [1.59, 4.71]。膝关节疼痛和膝关节 OA 症状与住院和死亡率无关。在吉隆坡的城市老年人群中,膝关节疼痛和膝关节 OA 症状与五年随访时可能出现肌少症的风险增加有关。未来的研究应设法找出膝关节OA患者发生肌肉疏松症的可调节风险因素。
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Risk of Sarcopenia, Hospitalization, and Mortality Among Malaysian Older Adults With Knee Pain: Five-Year Follow-up Study.

This study explores the longitudinal relationship between the presence of knee pain and knee osteoarthritis (OA) symptoms with risk of sarcopenia, hospitalization, and mortality. Data from Malaysian Elders Longitudinal Research (MELoR) study was utilized. The presence of knee pain and knee OA symptoms was determined at baseline between 2013 and 2015, whereas sarcopenia was determined in 2019 using SARC-F with telephone interviews. Hospitalization status was identified by asking participants "Have you been admitted to hospital since you enrolled into the MELoR study?" Death Registry data were obtained from the National Registry Department. Data from 577 individuals, mean age (SD) = 68.214 (7.095), range = 54 to 97 years, and 55.5% women at baseline, were included. Knee pain and knee OA symptoms were associated with increased risk of probable sarcopenia at follow-up, odds ratios (95% confidence interval) =2.71 [1.61, 4.58] and 2.73 [1.59, 4.71], respectively, after adjustment for confounders. Knee pain and knee OA symptoms were not associated with hospitalization and mortality. Knee pain and knee OA symptoms were associated with increased risk of probable sarcopenia at five-year follow-up in an urban older population in Kuala Lumpur. Future studies should seek to identify modifiable risk factors for the development of sarcopenia in individuals with knee OA.

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来源期刊
Asia-Pacific Journal of Public Health
Asia-Pacific Journal of Public Health 医学-公共卫生、环境卫生与职业卫生
CiteScore
3.30
自引率
4.00%
发文量
147
审稿时长
6 months
期刊介绍: Asia-Pacific Journal of Public Health (APJPH) is a peer-reviewed, bimonthly journal that focuses on health issues in the Asia-Pacific Region. APJPH publishes original articles on public health related issues, including implications for practical applications to professional education and services for public health and primary health care that are of concern and relevance to the Asia-Pacific region.
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